Inflammatory and apoptotic caspases are central players in inflammation and apoptosis,
respectively. However, recent studies have revealed that these caspases have functions …

Apoptosis is a major form of cell death, characterized initially by a series of stereotypic
morphological changes. In the nematode Caenorhabditis elegans, the gene ced-3 encodes …

▪ Abstract Apoptosis is a genetically programmed, morphologically distinct form of cell death
that can be triggered by a variety of physiological and pathological stimuli. Studies …

The concept of apoptotic cell death as an essential part of the development and life of
complex organisms has been devised in different situations and tested from various angles …

Caspases play an essential role during apoptotic cell death. These enzymes define a new
class of cysteine proteases and comprise a multi-gene family with more than a dozen distinct …

The caspase-3 (CPP32, apopain, YAMA) family of cysteinyl proteases has been implicated
as key mediators of apoptosis in mammalian cells. Gelsolin was identified as a substrate for …

Apoptosis or programmed cell death (PCD) is a genetically regulated, cellular suicide
mechanism that plays a crucial role in development and in the defense of homeostasis …

Both necrotic and apoptotic neuronal death are observed in various neurological and
neurodegenerative disorders. Calpain is activated in various necrotic and apoptotic …

The evolutionarily conserved execution phase of apoptosis is defined by characteristic
changes occurring during the final stages of death; specifically cell shrinkage, dynamic …

Apoptosis or programmed cell death is a process with typical morphological characteristics
including plasma membrane blebbing, cell shrinkage, chromatin condensation and …