Diltiazem: a review of its pharmacological properties and therapeutic efficacy

M Chaffman, RN Brogden - Drugs, 1985 - Springer
Diltiazem 1 is an orally and intravenously active calcium channel blocking agent shown to
be an effective and well-tolerated treatment for stable angina and angina due to coronary …

Nifedipine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related …

EM Sorkin, SP Clissold, RN Brogden - Drugs, 1985 - Springer
Nifedipine 1 is an antagonist of calcium influx through the slow channel of the cell
membrane and has been shown to be an effective and relatively well-tolerated treatment for …

A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their …

U Elkayam, J Amin, A Mehra, J Vasquez, L Weber… - Circulation, 1990 - Am Heart Assoc
We performed a prospective, randomized, double-blind, crossover study to compare the
efficacy and safety of vasodilation with the calcium entry blocker nifedipine with that of …

Verapamil: An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension

D McTavish, EM Sorkin - Drugs, 1989 - Springer
Although verapamil is a well-established treatment for angina, cardiac arrhythmias and
cardiomyopathies, this review reflects current interest in calcium antagonists as …

A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment

EA Ramoska, HA Spiller, M Winter, D Borys - Annals of emergency …, 1993 - Elsevier
Study objective: To examine the cardiovascular toxicity of calcium channel blockers and the
efficacy of various treatments. Design: Case series collected prospectively over one year …

Cellular mechanisms in shock and ischemia and their correction

IH Chaudry - American Journal of Physiology-Regulatory …, 1983 - journals.physiology.org
Various metabolic, cellular, and subcellular alterations in cell function and morphology occur
during shock or low flow conditions. Alterations in mitochondrial function during low flow …

Fatality from administration of labetalol and crushed extended-release nifedipine

JG Schier, MA Howland, RS Hoffman… - Annals of …, 2003 - journals.sagepub.com
Objective To report a case in which a crushed extended-release (XL) nifedipine tablet
contributed to a patient fatality. Case Summary A 38-year-old woman with multiple medical …

Assessment of hyperglycemia after calcium channel blocker overdoses involving diltiazem or verapamil

M Levine, EW Boyer, CN Pozner, AJ Geib… - Critical care …, 2007 - journals.lww.com
Background: Overdoses of calcium channel blocker agents result in hyperglycemia,
primarily due to the blockade of pancreatic L-type calcium channels and insulin resistance …

Verapamil intoxication: a literature review of overdoses and discussion of therapeutic options

CA Hofer, JK Smith, MF Tenholder - The American journal of medicine, 1993 - Elsevier
Calcium channel antagonists can be quite toxic. In the management of poisoning, early
recognition is critical. Calcium channel antagonists are frequently prescribed, and the …

Rapid photochemical inactivation of Ca2+-antagonists shows that Ca2+ entry directly activates contraction in frog heart

M Morad, YE Goldman, DR Trentham - Nature, 1983 - nature.com
Abstract 'Calcium-antagonists' are a group of pharmacological agents which are potent
vasodilators and are clinically used for the treatment of angina. They are thought to block …