siRNA versus miRNA as therapeutics for gene silencing
Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …
(miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently …
MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets
MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …
post-transcriptional regulation of gene expression. They have been implicated in the …
LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
L Chen, Y Zhou, H Li - Virus research, 2018 - Elsevier
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important
role in both normal biological activity and pathological processes such as viral infection and …
role in both normal biological activity and pathological processes such as viral infection and …
[HTML][HTML] MicroRNAs: role in hepatitis C virus pathogenesis
Hepatitis C virus (HCV) is a global health burden with an estimated 170–200 million peoples
chronically infected worldwide. HCV infection remains as an independent risk factor for …
chronically infected worldwide. HCV infection remains as an independent risk factor for …
Entry inhibitors: new advances in HCV treatment
XJ Qian, YZ Zhu, P Zhao, ZT Qi - Emerging microbes & infections, 2016 - Taylor & Francis
Hepatitis C virus (HCV) infection affects approximately 3% of the world's population and
causes chronic liver diseases, including liver fibrosis, cirrhosis, and hepatocellular …
causes chronic liver diseases, including liver fibrosis, cirrhosis, and hepatocellular …
[HTML][HTML] Exosomes containing miR-122-5p secreted by LPS-induced neutrophils regulate the apoptosis and permeability of brain microvascular endothelial cells by …
Q Li, A Nong, Z Huang, K He, Y Jia… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To explore the effect of exosomes containing miR-122-5p secreted by
lipopolysaccharide (LPS)-induced neutrophils on the apoptosis and permeability of brain …
lipopolysaccharide (LPS)-induced neutrophils on the apoptosis and permeability of brain …
[HTML][HTML] Dysregulated serum microRNA expression profile and potential biomarkers in hepatitis C virus-infected patients
S Zhang, X Ouyang, X Jiang, D Gu, Y Lin… - … journal of medical …, 2015 - ncbi.nlm.nih.gov
Objectives: Circulating microRNAs (miRNAs) play critical roles in pathogen-host
interactions. Aberrant miRNA expression profiles might have specific characteristics for virus …
interactions. Aberrant miRNA expression profiles might have specific characteristics for virus …
Gankyrin: a novel promising therapeutic target for hepatocellular carcinoma
P Zamani, M Matbou Riahi… - Artificial Cells …, 2018 - Taylor & Francis
Hepatocellular carcinoma (HCC) is known as fifth common malignancies and third common
cause of cancer-related death worldwide. The identification of various mechanisms which …
cause of cancer-related death worldwide. The identification of various mechanisms which …
MicroRNAs: New Therapeutic Targets for Familial Hypercholesterolemia?
Familial hypercholesterolemia (FH) is the most common inherited form of dyslipidemia and a
major cause of premature cardiovascular disease. Management of FH mainly relies on the …
major cause of premature cardiovascular disease. Management of FH mainly relies on the …
The involvement of microRNAs in HCV and HIV infection
N Joshi, M Chandane Tak… - … Advances in Vaccines …, 2022 - journals.sagepub.com
Approximately 2.3 million people are suffering from human immunodeficiency virus
(HIV)/hepatitis C virus (HCV) co-infection worldwide. Faster disease progression and …
(HIV)/hepatitis C virus (HCV) co-infection worldwide. Faster disease progression and …