Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook

H Li, H Kim, F Xu, J Han, Q Yao, J Wang, K Pu… - Chemical Society …, 2022 - pubs.rsc.org
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications

J Zielonka, J Joseph, A Sikora, M Hardy… - Chemical …, 2017 - ACS Publications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

Natural flavylium-inspired far-red to NIR-II dyes and their applications as fluorescent probes for biomedical sensing

Y Sun, P Sun, Z Li, L Qu, W Guo - Chemical Society Reviews, 2022 - pubs.rsc.org
Fluorescent probes that emit in the far-red (600–700 nm), first near-infrared (NIR-I, 700–900
nm), and second NIR (NIR-II, 900–1700 nm) regions possess unique advantages, including …

Organelle-targeting ratiometric fluorescent probes: design principles, detection mechanisms, bio-applications, and challenges

MK Goshisht, N Tripathi, GK Patra, M Chaskar - Chemical Science, 2023 - pubs.rsc.org
Biological species, including reactive oxygen species (ROS), reactive sulfur species (RSS),
reactive nitrogen species (RNS), F−, Pd2+, Cu2+, Hg2+, and others, are crucial for the …

Functional synthetic probes for selective targeting and multi-analyte detection and imaging

Y Yue, F Huo, F Cheng, X Zhu, T Mafireyi… - Chemical Society …, 2019 - pubs.rsc.org
In contrast to the classical design of a probe with one binding site to target one specific
analyte, probes with multiple interaction sites or, alternatively, with single sites promoting …

Hybrid rhodamine fluorophores in the visible/NIR region for biological imaging

L Wang, W Du, Z Hu, K Uvdal, L Li… - Angewandte Chemie …, 2019 - Wiley Online Library
Fluorophores and probes are invaluable for the visualization of the location and dynamics of
gene expression, protein expression, and molecular interactions in complex living systems …

The role of amino acids in neurotransmission and fluorescent tools for their detection

R Dalangin, A Kim, RE Campbell - International journal of molecular …, 2020 - mdpi.com
Neurotransmission between neurons, which can occur over the span of a few milliseconds,
relies on the controlled release of small molecule neurotransmitters, many of which are …

Recent advances in the development of responsive probes for selective detection of cysteine

R Zhang, J Yong, J Yuan, ZP Xu - Coordination Chemistry Reviews, 2020 - Elsevier
Cysteine (Cys), one of three endogenous biothiols, is involved in a variety of biological
processes, such as protein and peptide biosynthesis, enzyme active sites and cofactors, and …

Recent progress in the development of fluorescent probes for detection of biothiols

J Dai, C Ma, P Zhang, Y Fu, B Shen - Dyes and Pigments, 2020 - Elsevier
Biothiols derivatives including cysteine (Cys), homocysteine (Hcy), and glutathione (GSH)
play critical roles in maintaining physiological and pathological processes. Developing …