A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease

SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …

Exploring the Inhibitory Effects of Quinolone Medications on Carbonic Anhydrase Enzyme Activity: In Vitro and In Silico Investigation

Y Demir - ChemistrySelect, 2024 - Wiley Online Library
Enzyme inhibition is a frequently employed technique for regulating enzyme activity in
several biological systems that are physiologically significant. In this study, it was evaluated …

Synthesis, in vitro and docking studies of 2-substituted 5, 6, 7, 8-tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidine-4 (3H)-one derivatives as agents for the treatment of …

AS Chiriapkin, IP Kodonidi, DI Pozdnyakov… - Chimica Techno …, 2022 - journals.urfu.ru
Alzheimer's disease is a chronic neurodegenerative disease, which is characterized mainly
by a progressive decrease in intellectual abilities, memory impairment and a change in a …

Naphthoquinones and anthraquinones: Exploring their impact on acetylcholinesterase enzyme activity

HE Duran, Ş Beydemir - Biotechnology and Applied …, 2024 - Wiley Online Library
The identification of novel acetylcholinesterase inhibitors holds significant relevance in the
treatment of Alzheimer's disease (AD), the prevailing form of dementia. The exploration of …