Host-microbe interactions at the blood-brain barrier through the lens of induced pluripotent stem cell-derived brain-like endothelial cells
Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …
nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier …
Role of CARD9 in cell-and organ-specific immune responses in various infections
JS Lee, C Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
The caspase recruitment domain-containing protein 9 (CARD9) is an intracellular adaptor
protein that is abundantly expressed in cells of the myeloid lineage, such as neutrophils …
protein that is abundantly expressed in cells of the myeloid lineage, such as neutrophils …
Enterovirus A71 crosses a human blood–brain barrier model through infected immune cells
L Gaume, H Chabrolles, M Bisseux… - Microbiology …, 2024 - Am Soc Microbiol
ABSTRACT Enterovirus A71 (EV-A71) is associated with neurological conditions such as
acute meningitis and encephalitis. The virus is detected in the bloodstream, and high blood …
acute meningitis and encephalitis. The virus is detected in the bloodstream, and high blood …
Comprehensive study for synthesis, antiviral activity, docking and ADME study for the new fluorinated hydrazonal and indeno [1, 2-b] pyridine derivatives
In this context, we synthesized a novel series of fluorinated-indeno [1, 2-b] pyridin-5-one
derivatives 6a-h and used spectral and elemental studies to demonstrate their structural …
derivatives 6a-h and used spectral and elemental studies to demonstrate their structural …
Bioactive potentials of the truffle mushrooms Tirmania nivea, Tirmania pinoyi and Tuber indicum
WA Elkhateeb, AAF Soliman… - Egyptian …, 2024 - journals.lww.com
Background Truffles are ectomycorrhizal wild mushrooms that have ethnomycological
importance as a folklore remedy used to treat different skin and eye diseases and they are …
importance as a folklore remedy used to treat different skin and eye diseases and they are …
Common Chemical Plasticizer di (2-Ethhylhexyl) Phthalate 1 Exposure Exacerbates Coxsackievirus B3 Infection
R Kordbacheh, M Ashley, WD Cutts, TE Keyzer… - 2024 - preprints.org
Abstract Di (2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches
from plastic matrices and is under increasing scrutiny as numerous studies have linked it to …
from plastic matrices and is under increasing scrutiny as numerous studies have linked it to …
Gene therapy targeting the blood-brain barrier
J Körbelin, A Arrulo… - Vitamins and …, 2024 - pubmed.ncbi.nlm.nih.gov
Endothelial cells are the building blocks of vessels in the central nervous system (CNS) and
form the blood-brain barrier (BBB). An intact BBB limits permeation of large hydrophilic …
form the blood-brain barrier (BBB). An intact BBB limits permeation of large hydrophilic …