Poly-ε-caprolactone (PCL) is a biodegradable, biocompatible and semicrystalline polymer
having a very low glass transition temperature. Due to its slow degradation, PCL is ideally …

Nanoparticles are a drug delivery platform that can enhance the efficacy of active
pharmaceutical ingredients, including poorly-water soluble compounds, ionic drugs …

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

The emulsification is the first step of the emulsification solvent evaporation method and has
been extensively investigated. On the contrary the second step, the solvent transport out …

The aim of the current study was to design oral controlled release mucoadhesive
compressed hydrophilic matrices of atenolol and to optimize the drug release profile and …

This study investigates the release behavior of papaverine from poly (ε-caprolactone)(PCL)
microparticles prepared by the oil/water solvent evaporation method. Microparticles were …

The first study on application of Design of Experiments (DoE) in optimizing drug formulation
appeared in 1967. Since then the number of literature reports on the use of DoE optimization …

Quercetin had been shown to be effective in the management of arthritis. However,
bioavailability of quercetin is a concern for such treatment. This work aims at the …

This study developed an emulsion-solvent evaporation method for producing haloperidol-
loaded PLGA nanoparticles with up to 2%(wt/wt. of polymer) drug content, in vitro release …

Preparation, characterization and drug release behavior of loaded polybutyl adipate (PBA)
nanocapsules with penicillin-G are described here. The nanocapsules were produced using …