Spatial transcriptomics and the anatomical pathologist: Molecular meets morphology

JMB Pang, DJ Byrne, ART Bergin, F Caramia… - …, 2024 - Wiley Online Library
In recent years anatomical pathology has been revolutionised by the incorporation of
molecular findings into routine diagnostic practice, and in some diseases the presence of …

Novel combinatorial approaches to tackle the immunosuppressive microenvironment of prostate cancer

EG Shackleton, HY Ali, M Khan, GA Pockley… - Cancers, 2021 - mdpi.com
Simple Summary The mainstay of treatment for advanced prostate cancer (PCa) is androgen
deprivation therapy (ADT), and although patients initially respond, almost all will eventually …

Identification of prostate cancer bone metastasis related genes and potential therapy targets by bioinformatics and in vitro experiments

H Jiang, M Liu, Y Deng, C Zhang, L Dai… - Journal of Cellular …, 2024 - Wiley Online Library
The aetiology of bone metastasis in prostate cancer (PCa) remains unclear. This study aims
to identify hub genes involved in this process. We utilized machine learning, GO, KEGG …

Typical and atypical carcinoid tumors of the mediastinum: a biomarker analysis of 27 cases with clinical correlation

M Zaleski, N Kalhor, CA Moran - International Journal of …, 2021 - journals.sagepub.com
Thymic typical and atypical carcinoids are rare and appear to be more aggressive than
similar tumors in other sites. We retrospectively analyzed a group of biomarkers that hold …

Tumor-Nerve Interface: An Emerging Therapeutic Intervention Point for Solid Cancers

A Krishnan - 2022 - Springer
Accumulating research in the past decade has shown that peripheral nerves in the tumor
microenvironment have an immense potential to modulate tumor growth and metastasis …

[PDF][PDF] Novel Combinatorial Approaches to Tackle the Immunosuppressive Microenvironment of Prostate Cancer. Cancers 2021, 13, 1145

EG Shackleton, HY Ali, M Khan, GA Pockley… - 2021 - academia.edu
Prostate cancer (PCa) is the second-most common cancer in men worldwide and treatment
options for patients with advanced or aggressive prostate cancer or recurrent disease …

Rôles de la méthyltransférase EZH2 et de la déméthylase JMJD3 sur la régulation de la marque H3K27me3 dans le cancer de la prostate

A Sanchez - 2022 - theses.hal.science
Le cancer de la prostate est le deuxième cancer le plus fréquent chez l'homme dans le
monde. Les changements épigénétiques en réponse à des événements externes …

[图书][B] Transcriptional Signatures of the Tumor and the Tumor Microenvironment Predict Cancer Patient Outcomes

V Friedl - 2021 - search.proquest.com
Predicting the most effective cancer therapy for patients is a challenging yet very important
task. In my doctoral thesis, I describe new insights gained from using transcriptional …