The impact of orphan histidine kinases and phosphotransfer proteins on the regulation of clostridial sporulation initiation
Sporulation is an important feature of the clostridial life cycle, facilitating survival of these
bacteria in harsh environments, contributing to disease transmission for pathogenic species …
bacteria in harsh environments, contributing to disease transmission for pathogenic species …
The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system
AN Edwards, SM McBride - PLoS Genetics, 2023 - journals.plos.org
The ability to form a dormant spore is essential for the survival of the anaerobic pathogen,
Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of …
Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of …
Regulatory Networks: Linking Toxin Production and Sporulation in Clostridioides difficile
Clostridioides difficile has been recognized as an important nosocomial pathogen that
causes diarrheal disease as a consequence of antibiotic exposure and costs the healthcare …
causes diarrheal disease as a consequence of antibiotic exposure and costs the healthcare …
The predicted acetoin dehydrogenase pathway represses sporulation of Clostridioides difficile
Clostridioides difficile is a major gastrointestinal pathogen that is transmitted as a dormant
spore. As an intestinal pathogen, C. difficile must contend with variable environmental …
spore. As an intestinal pathogen, C. difficile must contend with variable environmental …