Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells
undergoing a defective differentiation due to genomic and epigenetic impairments …

Robust brain development requires the tight coordination between tissue growth, neuronal
differentiation and stem cell maintenance. To achieve this, neural stem cells need to balance …

Axial development of mammals involves coordinated morphogenetic events, including axial
elongation, somitogenesis, and neural tube formation. To gain insight into the signals …

Simple Summary Neuroblastoma is a tumor of the sympathetic nervous system that
substantially contributes to childhood cancer mortality. Neuroblastoma originates from the …

Neural stem cell (NSC) populations persist in the adult vertebrate brain over a lifetime, and
their homeostasis is controlled at the population level through unknown mechanisms. Here …

The transcription factor Sox11 plays important roles in retinal neurogenesis during
vertebrate eye development. However, its function in retina regeneration remains elusive …

Neural stem cells (NSCs) are progenitor cell populations generating glial cells and neurons
and endowed with long-lasting self-renewal and differentiation potential. While some neural …

Brain neurons arise from relatively few progenitors generating an enormous diversity of
neuronal types. Nonetheless, a cardinal feature of mammalian brain neurogenesis is …

Early-life lead (Pb) exposure has been linked to adverse neurodevelopmental outcomes.
Recent evidence has indicated a critical role of DNA methylation (DNAm) in cognition, and …

Primary cilia (PC) are solitary, post-mitotic, microtubule-based, and membrane-covered
protrusions that are found on almost every mammalian cell. PC are specialized cellular …