Neuronal communication crucially relies on exocytosis of neurotransmitters from synaptic
vesicles (SVs) which are clustered at synapses. To ensure reliable neurotransmitter release …

Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …

Neuronal transmission relies on the regulated secretion of neurotransmitters, which are
packed in synaptic vesicles (SVs). Hundreds of SVs accumulate at synaptic boutons …

Cells compartmentalize parts of their interiors into liquid-like condensates, which can be
reconstituted in vitro. Although these condensates interact with membrane-bound …

Membraneless liquid compartments based on phase-separating biopolymers have been
observed in diverse cell types and attributed to weak multivalent interactions predominantly …

Many membraneless organelles are liquid-like domains that form inside the active,
viscoelastic environment of living cells through phase separation. To investigate the …

Microtubule organization in cells relies on targeting mechanisms. Cytoplasmic linker
proteins (CLIPs) and CLIP-associated proteins (CLASPs) are key regulators of microtubule …

Liquid-liquid phase separation (LLPS) is emerging as a major principle for the mesoscale
organization of proteins, RNAs, and membrane-bound organelles into biomolecular …

In addition to long-distance molecular motor-mediated transport, cellular vesicles also need
to be moved at short distances with defined directions to meet functional needs in …

Liquid–liquid phase separation is a major mechanism for organizing macromolecules,
particularly proteins with intrinsically disordered regions, in compartments not limited by a …