Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since
the early history of cryopreservation. It has been used for decades in many thousands of cell …
the early history of cryopreservation. It has been used for decades in many thousands of cell …
To protect and to preserve: novel preservation strategies for extracellular vesicles
Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by
stem cells exert similar therapeutic effects and these have been proposed as an alternative …
stem cells exert similar therapeutic effects and these have been proposed as an alternative …
Biomanufacturing for clinically advanced cell therapies
The achievements of cell-based therapeutics have galvanized efforts to bring cell therapies
to the market. To address the demands of the clinical and eventual commercial-scale …
to the market. To address the demands of the clinical and eventual commercial-scale …
[HTML][HTML] Effects of storage media, supplements and cryopreservation methods on quality of stem cells
Despite a vast amount of different methods, protocols and cryoprotective agents (CPA), stem
cells are often frozen using standard protocols that have been optimized for use with cell …
cells are often frozen using standard protocols that have been optimized for use with cell …
Biobanking of human mesenchymal stem cells: future strategy to facilitate clinical applications
KW Yong, JR Choi, WKZ Wan Safwani - Biobanking and cryopreservation …, 2016 - Springer
Human mesenchymal stem cells (hMSCs), a type of adult stem cells that hold great potential
in clinical applications (eg, regenerative medicine and cell-based therapy) due to their ability …
in clinical applications (eg, regenerative medicine and cell-based therapy) due to their ability …
[HTML][HTML] Cellhesion VP enhances the immunomodulating potential of human mesenchymal stem cell-derived extracellular vesicles
ES Kim, K Kida, J Mok, Y Seong, SY Jo, T Kanaki… - Biomaterials, 2021 - Elsevier
Mesenchymal stem cell (MSC) transplantation is a promising therapy for regenerative
medicine. However, MSCs grown under two-dimensional (2D) culture conditions differ …
medicine. However, MSCs grown under two-dimensional (2D) culture conditions differ …
In vitro differentiation of single donor derived human dental mesenchymal stem cells into pancreatic β cell-like cells
The present study was carried out to investigate and compare the in vitro differentiation
potential of mesenchymal stem cells (MSCs) isolated from human dental tissues (pulp …
potential of mesenchymal stem cells (MSCs) isolated from human dental tissues (pulp …
Novel Cryopreservation Approach Providing Off‐the‐Shelf Availability of Human Multipotent Mesenchymal Stromal Cells for Clinical Applications
O Rogulska, O Tykhvynska, O Revenko… - Stem Cells …, 2019 - Wiley Online Library
Cryopreservation is the only established method to provide long‐term storage and fast
availability of cellular product for therapeutic applications. The overwhelming majority of …
availability of cellular product for therapeutic applications. The overwhelming majority of …
Cytochalasin-B-inducible nanovesicle mimics of natural extracellular vesicles that are capable of nucleic acid transfer
A Oshchepkova, A Neumestova, V Matveeva… - Micromachines, 2019 - mdpi.com
Extracellular vesicles provide cell-to-cell communication and have great potential for use as
therapeutic carriers. This study was aimed at the development of an extracellular vesicle …
therapeutic carriers. This study was aimed at the development of an extracellular vesicle …
Assessment of post-thaw quality of dental mesenchymal stromal cells after long-term cryopreservation by uncontrolled freezing
Cryopreservation abilities of dental tissue-derived mesenchymal stromal cells (DMSCs)
including dental pulp stem cells (DPSCs) and dental follicle stem cells (DFSC) play an …
including dental pulp stem cells (DPSCs) and dental follicle stem cells (DFSC) play an …