The neurobiology of depression: An integrated view

J Dean, M Keshavan - Asian journal of psychiatry, 2017 - Elsevier
Abstract Major Depressive Disorder (MDD) is one of the most common and debilitating
mental disorders; however, its etiology remains unclear. This paper aims to summarize the …

[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal

R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration

CIF Janssen, AJ Kiliaan - Progress in lipid research, 2014 - Elsevier
Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated
fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Docosahexaenoic and arachidonic acids as neuroprotective nutrients throughout the life cycle

V Sambra, F Echeverria, A Valenzuela… - Nutrients, 2021 - mdpi.com
The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and
brain development throughout the life cycle is fundamental. DHA and AA are long-chain …

Neuroinflammation and neurodegeneration in overnutrition-induced diseases

D Cai - Trends in Endocrinology & Metabolism, 2013 - cell.com
Overnutrition-induced diseases such as obesity and type 2 diabetes (T2D) involve neural
dysregulation of metabolic physiology. Recently, interdisciplinary research in neuroscience …

Hypothalamic inflammation in the control of metabolic function

M Valdearcos, AW Xu, SK Koliwad - Annual review of …, 2015 - annualreviews.org
Diet-induced obesity leads to devastating and common chronic diseases, fueling ongoing
interest in determining new mechanisms underlying both obesity and its consequences. It is …

[HTML][HTML] Differentiating the influence of sedentary behavior and physical activity on brain health in late adulthood

AM Collins, C Molina-Hidalgo, SL Aghjayan… - Experimental …, 2023 - Elsevier
Public health messaging calls for individuals to be more physically active and less
sedentary, yet these lifestyle behaviors have been historically studied independently. Both …

Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer's …

O Busquets, M Ettcheto, M Pallàs, C Beas-Zarate… - Mechanisms of ageing …, 2017 - Elsevier
Aims The sporadic and late-onset form of Alzheimer's disease (AD) constitutes the most
common form of dementia. This non-familiar form could be a consequence of metabolic …

Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral …

ME de Sousa Rodrigues, M Bekhbat… - Brain, Behavior, and …, 2017 - Elsevier
The mechanisms underlying the association between chronic psychological stress,
development of metabolic syndrome (MetS), and behavioral impairment in obesity are …