The lungs are a major site of entry of pathogens into the body and thus require rapid and
effective innate responses to prevent pathogens establishing infection and to limit their …

Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia (IIP), is characterized by irreversible scarring of the lung parenchyma and …

Pulmonary ischemia-reperfusion injury (IRI) is a clinical syndrome of acute lung injury that
occurs after lung transplantation or remote organ ischemia. IRI causes early mortality and …

The lung offers one of the largest exchange surfaces of the individual with the elements of
the environment. As a place of important interactions between self and non-self, the lung is …

There is clear evidence that environmental exposures and genetic predisposition contribute
to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Cigarette smoking increases the …

Background Fibrotic idiopathic interstitial pneumonias (fIIP) are a group of fatal lung
diseases with largely unknown etiology and without definitive treatment other than lung …

Pulmonary fibrosis is a form of lung disease that develops due to aberrant wound-healing
following repeated alveoli injury in genetically susceptible individuals, resulting in chronic …

Rationale: Disease activity in idiopathic pulmonary fibrosis (IPF) remains highly variable,
poorly understood, and difficult to predict. Objectives: To identify a predictor using short-term …

The lungs are continuously subjected to environmental insults making them susceptible to
infection and injury. They are protected by the respiratory epithelium, which not only serves …

Interstitial lung disease (ILD) is a heterogeneous group of diseases characterized by lung
injury caused by lung fibroblast proliferation, interstitial inflammation, and fibrosis. Different …