Context The persistent spread of highly contagious COVID-19 disease is one of the deadliest occurrences in the history of mankind. Despite the distribution of numerous …
CM Hamadani, F Mahdi, A Merrell, J Flanders… - Advanced …, 2024 - Wiley Online Library
Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge. For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately …
Two chemical motifs of interest for medicinal chemistry, silatrane as 1-(3-aminopropyl) silatrane (SIL M), and nitro group attached in position 5 to salicylaldehyde, are coupled in a …
A class I histone deacetylase HDAC8 is associated with several diseases, including cancer, intellectual impairment and parasite infection. Most of the HDAC inhibitors that have so far …
Biocompatible cholinium-based ionic liquids (ILs) are used extensively in the pharmaceutical and biomedical industries. To enhance structural stability and solubility of …
Choline geranate (CAGE) ionic liquids (ILs) stabilize insulin, thereby aiding its oral delivery, whereas ethanol (EtOH) affects its stability by disrupting the hydrophobic interactions. In this …
Respiratory illness due to SARS-CoV-2 emerged in 2019 and has a significant morbidity and mortality rate. The main protease (Mpro) is mainly responsible for viral replications …
HT Mathew, K Abhisek, SS Vhatkar… - Handbook of Ionic …, 2024 - Wiley Online Library
The implementation of cleaner and greener methods has aided in sustainability and alleviating chemical toxicity. Among many such implementations, ionic liquids (IL) were seen …