Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?

D Pakotiprapha, S Kuhaudomlarp, R Tinikul… - Viruses, 2023 - mdpi.com
African swine fever (ASF) is a highly contagious and economically devastating disease
affecting domestic pigs and wild boar, caused by African swine fever virus (ASFV). Despite …

Bioprospecting phytochemicals of Rosmarinus officinalis L. for targeting SARS-CoV-2 main protease (Mpro): a computational study

U Patel, K Desai, RC Dabhi, JJ Maru… - Journal of Molecular …, 2023 - Springer
Context The persistent spread of highly contagious COVID-19 disease is one of the
deadliest occurrences in the history of mankind. Despite the distribution of numerous …

Ionic Liquid Coating‐Driven Nanoparticle Delivery to the Brain: Applications for NeuroHIV

CM Hamadani, F Mahdi, A Merrell, J Flanders… - Advanced …, 2024 - Wiley Online Library
Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge.
For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately …

A Comprehensive Review on Imperative Role of Ionic Liquids in Pharmaceutical Sciences

P Uniyal, S Das, S Panwar, N Kukreti… - Current Drug …, 2024 - ingentaconnect.com
CDD-Content Vol-21-9 Page 1 Current Drug Delivery ISSN: 1567-2018 eISSN: 1875-5704
ImpactFactor:2.4 BENTHAMSCIENCE Arrector pili muscleSebaceous glandSweat gland …

Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic–Inorganic Structure with High Medicinal Significance

MF Zaltariov, M Turtoi, D Peptanariu, AM Macsim… - Pharmaceutics, 2022 - mdpi.com
Two chemical motifs of interest for medicinal chemistry, silatrane as 1-(3-aminopropyl)
silatrane (SIL M), and nitro group attached in position 5 to salicylaldehyde, are coupled in a …

Discovery of novel HDAC8 inhibitors from natural compounds by in silico high throughput screening

SM Esther Rubavathy, K Palanisamy… - Journal of …, 2023 - Taylor & Francis
A class I histone deacetylase HDAC8 is associated with several diseases, including cancer,
intellectual impairment and parasite infection. Most of the HDAC inhibitors that have so far …

Effect of mixtures of ionic liquids and water on the structure and stability of the insulin dimer: a combined DFT and MD simulation study

NG Lakshman, SME Rubavathy, S Priyankha… - New Journal of …, 2023 - pubs.rsc.org
Biocompatible cholinium-based ionic liquids (ILs) are used extensively in the
pharmaceutical and biomedical industries. To enhance structural stability and solubility of …

Counteractive Effects of Choline Geranate (CAGE) ILs and Ethanol on Insulin's Stability—A Leap Forward towards Oral Insulin Formulation

K Palanisamy, M Prakash - Molecules, 2022 - mdpi.com
Choline geranate (CAGE) ionic liquids (ILs) stabilize insulin, thereby aiding its oral delivery,
whereas ethanol (EtOH) affects its stability by disrupting the hydrophobic interactions. In this …

In silico screening of potential antiviral inhibitors against SARS-CoV-2 main protease

K Palanisamy, KR Maiyelvaganan… - Molecular …, 2023 - Taylor & Francis
Respiratory illness due to SARS-CoV-2 emerged in 2019 and has a significant morbidity
and mortality rate. The main protease (Mpro) is mainly responsible for viral replications …

Ionic Liquids as Green Solvents: Are Ionic Liquids Nontoxic and Biodegradable?

HT Mathew, K Abhisek, SS Vhatkar… - Handbook of Ionic …, 2024 - Wiley Online Library
The implementation of cleaner and greener methods has aided in sustainability and
alleviating chemical toxicity. Among many such implementations, ionic liquids (IL) were seen …