[HTML][HTML] Roles and mechanisms of copper homeostasis and cuproptosis in osteoarticular diseases

J Han, J Luo, C Wang, L Kapilevich, X Zhang - Biomedicine & …, 2024 - Elsevier
Copper is an essential trace element in the human body that is extensively distributed
throughout various tissues. The appropriate level of copper is crucial to maintaining the life …

[HTML][HTML] Disulfiram exerts antifibrotic and anti-inflammatory therapeutic effects on perimysial orbital fibroblasts in Graves' orbitopathy

X Wang, H Ye, S Yang, X Sha, X Wang… - International Journal of …, 2022 - mdpi.com
Fibrosis of extraocular muscles (EOMs) is a marker of end-stage in Graves' orbitopathy (GO).
To determine the antifibrotic and anti-inflammatory therapeutic effects and the underlying …

Reactive Oxygen Species‐Responsive Nanoparticles Toward Extracellular Matrix Normalization for Pancreatic Fibrosis Regression

L Qi, BW Duan, H Wang, YJ Liu, H Han… - Advanced …, 2024 - Wiley Online Library
Pancreatic fibrosis (PF) is primarily characterized by aberrant production and degradation
modes of extracellular matrix (ECM) components, resulting from the activation of pancreatic …

Melatonin Attenuates Extracellular Matrix Accumulation and Cardiac Injury Manifested by Copper

SA Ali, S ‬‬‬‬‬‬‬ Bommaraju, J Patwa, P Khare… - … Trace Element Research, 2023 - Springer
Copper-induced cardiac injury is not widely reported in spite of its ability to cause oxidative
damage and tissue injury. Structural and morphological changes in the cardiac tissue are …