A key challenge in molecular biology is to decipher the mapping of protein sequence to
function. To perform this mapping requires the identification of sequence features most …

The expression of a few key genes determines the body plan of the fruit fly. We show that the
spatial expression patterns for several of these genes scale precisely with embryo size …

Animal morphogenesis, the development of an organism's body form, is commonly
perceived as a directed and almost deterministic process. However, noise and stochastic …

A key feature of many developmental systems is their ability to self-organize spatial patterns
of functionally distinct cell fates. To ensure proper biological function, such patterns must be …

Fig. 1. The expression profiles of gap and pair-rule genes scale with the length of the
embryo L despite the fact that their maternal inputs do not exhibit such scaling. When plotted …

Individual components such as cells, particles, or agents within a larger system often require
detailed understanding of their relative position to act accordingly, enabling the system as a …