Proteoforms, which arise from post-translational modifications, genetic polymorphisms and
RNA splice variants, play a pivotal role as drivers in biology. Understanding proteoforms is …

Native top-down mass spectrometry (nTDMS) allows characterization of protein structure
and noncovalent interactions with simultaneous sequence mapping and proteoform …

The characterization of protein complex is vital for unraveling biological mechanisms in
various life processes. Despite advancements in biophysical tools, the capture of non …

Native top-down mass spectrometry (nTDMS) has emerged as a powerful structural biology
tool that can localize post-translational modifications (PTMs), explore ligand-binding …

Knotted proteins are fascinating natural biomolecules whose backbones entangle
themselves in a knot. Their particular knotted configurations provide them with a wide range …

S-glutathionylation (SSG) is increasingly recognized as a critical signaling mechanism in the
heart, yet SSG modifications in cardiac sarcomeric proteins remain understudied. Here we …