Modified nucleotides in tRNA are critical components of the translation apparatus, but their
importance in the process of translational regulation had until recently been greatly …

Successful pathogens must be able to adapt to a multitude of stressors imposed by their
host. Acinetobacter baumannii has emerged as a major global health threat due to its …

Abstract In bacterial tRNAs, 5-carboxymethoxyuridine (cmo5U) and its derivatives at the first
position of the anticodon facilitate non-Watson–Crick base pairing with guanosine and …

Extensive knowledge of both the nature and position of tRNA modifications in all cellular
tRNAs has been limited to two bacteria, Escherichia coli and Mycoplasma capricolum …

Acyltransferases (AT) are enzymes that catalyze the transfer of acyl group to a receptor
molecule. This review focuses on ATs that act on thioester‐containing substrates. Although …

Catechol O-methyltransferase (COMT) is widely distributed in nature and installs a methyl
group onto one of the vicinal hydroxyl groups of a catechol derivative. Enzymes belonging to …

Posttranscriptional modifications of tRNA are widely conserved in all domains of life.
Especially, those occurring within the anticodon often modulate translational efficiency …

In bacteria, tRNAs that decode 4-fold degenerate family codons and have uridine at position
34 of the anticodon are typically modified with either 5-methoxyuridine (mo5U) or 5 …

The Zika virus (ZIKV) outbreak in 2015–2016 raised public health concerns and created a
pressing need for vaccine development. However, no vaccine has been developed and …

Bacterial biofilm is resistant to conventional antibiotic treatments, leading to complications
associated with many infection-related human diseases. Epigallocatechin Gallate (EGCG), a …