Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2015 - pubs.rsc.org
Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

Biological activity of recently discovered halogenated marine natural products

GW Gribble - Marine drugs, 2015 - mdpi.com
This review presents the biological activity—antibacterial, antifungal, anti-parasitic, antiviral,
antitumor, antiinflammatory, antioxidant, and enzymatic activity—of halogenated marine …

Chemistry, biosynthesis and biological activity of terpenoids and meroterpenoids in bacteria and fungi isolated from different marine habitats

M Gozari, M Alborz, HR El-Seedi, AR Jassbi - European Journal of …, 2021 - Elsevier
The marine environment with its vast biological diversity encompasses many organisms that
produce bioactive natural products. Marine microorganisms are rich sources of compounds …

From genomics to metabolomics, moving toward an integrated strategy for the discovery of fungal secondary metabolites

T Hautbergue, EL Jamin, L Debrauwer, O Puel… - Natural Product …, 2018 - pubs.rsc.org
Fungal secondary metabolites are defined by bioactive properties that ensure adaptation of
the fungus to its environment. Although some of these natural products are promising …

Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin

R Nicoletti, A Trincone - Marine drugs, 2016 - mdpi.com
In recent years, the search for novel natural compounds with bioactive properties has
received a remarkable boost in view of their possible pharmaceutical exploitation. In this …

Anticancer and Antifungal Compounds from Aspergillus, Penicillium and Other Filamentous Fungi

TT Bladt, JC Frisvad, PB Knudsen, TO Larsen - Molecules, 2013 - mdpi.com
This review covers important anticancer and antifungal compounds reported from
filamentous fungi and in particular from Aspergillus, Penicillium and Talaromyces. The …

Epoxide containing molecules: A good or a bad drug design approach

AR Gomes, CL Varela, EJ Tavares-da-Silva… - European journal of …, 2020 - Elsevier
Functional group modification is one of the main strategies used in drug discovery and
development. Despite the controversy of being identified for many years as a biologically …

Structures and bioactivities of secondary metabolites from Penicillium genus since 2010

X Zhang, Q Yin, X Li, X Liu, H Lei, B Wu - Fitoterapia, 2022 - Elsevier
Penicillium genus was a fungal endophyte first reported by Alexander Fleming in 1928 and
attracted more attention in recent decades due to its multitudinous metabolites which …

Toward a cancer drug of fungal origin

A Kornienko, A Evidente, M Vurro… - Medicinal research …, 2015 - Wiley Online Library
Although fungi produce highly structurally diverse metabolites, many of which have served
as excellent sources of pharmaceuticals, no fungi‐derived agent has been approved as a …

Integrating Molecular Networking and 1H NMR To Target the Isolation of Chrysogeamides from a Library of Marine-Derived Penicillium Fungi

XM Hou, YY Li, YW Shi, YW Fang, R Chao… - The Journal of …, 2019 - ACS Publications
A challenging problem in natural product discovery is to rapidly dereplicate known
compounds and expose novel ones from complicated components. Herein, integrating the …