Light-scattering methods for tissue diagnosis

ZA Steelman, DS Ho, KK Chu, A Wax - Optica, 2019 - opg.optica.org
Light scattering has become a common biomedical research tool, enabling diagnostic
sensitivity to myriad tissue alterations associated with disease. Light–tissue interactions are …

Integrated optical system and components utilizing tunable optical sources and coherent detection and phased array for imaging, ranging, sensing, communications …

E Swanson - US Patent 9,683,928, 2017 - Google Patents
An integrated optical system includes a photonic integrated circuit (PIC) having a frequency
tunable optical source, a coherent optical receiver, and an optical phased array for coupling …

Light detection and ranging system with photonic integrated circuit

E Swanson - US Patent 10,627,485, 2020 - Google Patents
Disclosed herein are optical integration technologies, designs, systems and methods
directed toward Optical Coherence Tomography (OCT) and other interferometric optical …

Wavelength-dependent optical properties of melanosomes in retinal pigmented epithelium and their changes with melanin bleaching: a numerical study

W Song, L Zhang, S Ness, J Yi - Biomedical optics express, 2017 - opg.optica.org
In this paper, we present the first numerical study on full metrics of wavelength-dependent
optical properties of melanosomes in retinal pigmented epithelial (RPE) cells. T-matrix …

Two‐dimensional light scattering anisotropy cytometry for label‐free classification of ovarian cancer cells via machine learning

X Su, T Yuan, Z Wang, K Song, R Li, C Yuan… - Cytometry Part …, 2020 - Wiley Online Library
We develop a single‐mode fiber‐based cytometer for the obtaining of two‐dimensional (2D)
light scattering patterns from static single cells. Anisotropy of the 2D light scattering patterns …

Accurate measurement of volume and shape of resting and activated blood platelets from light scattering

AE Moskalensky, MA Yurkin… - … of biomedical optics, 2013 - spiedigitallibrary.org
We introduce a novel approach for determination of volume and shape of individual blood
platelets modeled as an oblate spheroid from angle-resolved light scattering with flow …

Optical measurement system using multicore optical fiber

E Swanson - US Patent 10,895,525, 2021 - Google Patents
An optical-fiber measurement system includes an optical system that generates light and a
spatial optical switch that is coupled to the optical system that processes the light generated …

T-matrix formulation of electromagnetic wave scattering by charged non-spherical scatterers

H Zhong, L Xie, J Zhou - Journal of Quantitative Spectroscopy and …, 2020 - Elsevier
In this paper, a method is proposed to solve the scattering of electromagnetic waves (EMWs)
by a uniformly charged non-spherical scatterer. Based on Waterman's extended boundary …

Optical Thromboelastography to evaluate whole blood coagulation

Z Hajjarian, MM Tripathi, SK Nadkarni - Journal of biophotonics, 2015 - Wiley Online Library
Measurement of blood viscoelasticity during clotting provides a direct metric of haemostatic
conditions. Therefore, technologies that quantify blood viscoelasticity at the point‐of‐care …

Automatic classification of label‐free cells from small cell lung cancer and poorly differentiated lung adenocarcinoma with 2D light scattering static cytometry and …

H Wei, L Xie, Q Liu, C Shao, X Wang, X Su - Cytometry Part A, 2019 - Wiley Online Library
Small cell lung cancer (SCLC) needs to be classified from poorly differentiated lung
adenocarcinoma (PDLAC) for appropriate treatment of lung cancer patients. Currently, the …