The management of patients with autoimmune rheumatic diseases such as rheumatoid
arthritis (RA) remains a significant challenge. Often the rheumatologist is restricted to …

Many diseases appear to be caused by the misregulation of protein maintenance. Such
diseases of protein homeostasis, or “proteostasis,” include loss-of-function diseases (cystic …

Aim: Achieving reliably high production of reactive oxygen species (ROS) in photodynamic
therapy (PDT) remains challenging. Graphene quantum dots (GQDs) hold great promise for …

Oxidative stress resulting from excessive free-radical release is likely implicated in the
initiation and progression of epilepsy. Therefore, antioxidant therapies aimed at reducing …

Epilepsy is considered one of the most common neurological disorders worldwide. Oxidative
stress produced by free radicals may play a role in the initiation and progression of epilepsy; …

During physiological processes molecules undergo chemical changes involving reducing
and oxidizing reactions. A molecule with an unpaired electron can combine with a molecule …

The basic pathophysiology of epilepsy is still not fully understood. Epidemiological evidence
for epilepsy seems to suggest that it may not only be the propensity for seizures to occur …

Living cells maintain a balance between oxidation and reduction, and perturbations of this
redox balance are thought to contribute to various diseases. Recent attempts to regulate …

Recently higher rates of autism diagnosis suggest involvement of environmental factors in
causing this developmental disorder, in concert with genetic risk factors. Autistic children …

Protein misfolding is a common event in living cells. In young and healthy cells, the
misfolded protein load is disposed of by protein quality control (PQC) systems. In aging cells …