Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I–IV studies from Clinicaltrials.gov

NA Obaid - Frontiers in Microbiology, 2024 - frontiersin.org
Background Fecal microbiota transplantation (FMT) is an interventional approach to treat
chronic and recurrent Clostridioides difficile infection (CDI). However, there is insufficient …

[HTML][HTML] Therapeutics involved in managing initial and recurrent Clostridium difficile infection: An updated literature review

VK Nagesh, HHV Tran, D Elias… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Clostridium difficile infection (CDI) has been increasing due to the effect of recurrent
hospitalizations. The use of antibiotics has been shown to alter the gut microbiome and lead …

[HTML][HTML] Validation of Lyophilized Human Fecal Microbiota for the Treatment of Clostridioides difficile Infection: A Pilot Study with Pharmacoeconomic Analysis of a …

CH Yamada, GB Ortis, GM Buso, TC Martins… - Microorganisms, 2024 - mdpi.com
Background: Clostridioides difficile infection (CDI) represents a prevalent and potentially
severe health concern linked to the usage of broad-spectrum antibiotics. The aim of this …

Clostridioides Difficile: A Concise Review of Best Practices and Updates

A Yakout, Y Bi, DM Harris - Journal of Primary Care & …, 2024 - journals.sagepub.com
Clostridioides difficile infection (CDI) is one of the most common and severe nosocomial
infections worldwide. It can also affect healthy individuals in the community. The incidence of …

The evolving landscape of live biotherapeutics in the treatment of Clostridioides difficile infection

P Berry, S Khanna - Indian Journal of Gastroenterology, 2025 - Springer
Clostridioides difficile (C. difficile) infection (CDI) is common after antibiotic exposure and
presents significant morbidity, mortality and healthcare costs worldwide. The rising …

Clostridioides difficile infection in the allogeneic hematopoietic cell transplant recipient

D Lo Porto, A Mularoni, E Castagnola… - Transplant Infectious …, 2023 - Wiley Online Library
Clostridioides difficile (CD) is one of the most important causes of diarrhea in hospitalized
patients, in particular those who undergo an allogeneic hematopoietic cell transplant (allo …

The Progression of Microbiome Therapeutics for the Management of Gastrointestinal Diseases and Beyond

JR Allegretti, S Khanna, BH Mullish, P Feuerstadt - Gastroenterology, 2024 - Elsevier
There has been an increased ability to investigate human microbiota through next
generation sequencing and functional assessment. This advancement has rapidly …

[HTML][HTML] Colonization and Changes in Potential Functionality of the Bacterial Population in Fecal Microbiota Transplantation

A Hartikainen - 2024 - helda.helsinki.fi
The human microbiota consists of trillions of microbes that inhabit different parts of the body.
Most of them are bacteria that reside in the gastrointestinal tract, a place for complex …