KIR-HLA gene diversities and susceptibility to lung cancer
Killer-cell immunoglobulin-like receptors (KIR) are essential for acquiring natural killer (NK)
cell effector function, which is modulated by a balance between the net input of signals …
cell effector function, which is modulated by a balance between the net input of signals …
Coexistence of inhibitory and activating killer-cell immunoglobulin-like receptors to the same cognate HLA-C2 and Bw4 ligands confer breast cancer risk
Human leukocyte antigen (HLA) class I-specific killer-cell immunoglobulin-like receptors
(KIR) regulate natural killer (NK) cell function in eliminating malignancy. Breast cancer (BC) …
(KIR) regulate natural killer (NK) cell function in eliminating malignancy. Breast cancer (BC) …
Large case-control study indicates no association of KIR genotype and risk of developing acute myeloid leukemia
F Heidenreich, B Falk, H Baldauf, C Massalski… - Blood …, 2023 - ashpublications.org
Immunogenetic association studies may give rise to new hypotheses on the immune
surveillance of cancer. We hypothesized that certain combinations of killer immunoglobulin …
surveillance of cancer. We hypothesized that certain combinations of killer immunoglobulin …
Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer
Z Shiravani, K Mirshekari, MH Larki, N Shafiee… - Journal of Reproductive …, 2024 - Elsevier
Endometrial cancer (EC) constitutes more than half of all genital cancers in women, with an
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …
KIR-HLA functional repertoire influences trastuzumab efficiency in patients with HER2-positive breast cancer
E Muraro, M De Zorzi, G Miolo, D Lombardi… - Frontiers in …, 2022 - frontiersin.org
Trastuzumab induced a high rate of pathological Complete Response (pCR) in patients
affected by locally advanced HER2-positive Breast Cancer (HER2-BC), by exploiting …
affected by locally advanced HER2-positive Breast Cancer (HER2-BC), by exploiting …
Understanding the killer-cell immunoglobulin like receptor polymorphism in retinoblastoma
R Aggarwal, M Sharma, U Singh, K Poulton… - Ophthalmic …, 2023 - Taylor & Francis
Background The KIR receptors present on the natural killer (NK) cells play a crucial role by
exercising cytotoxicity to eliminate tumor cells. Both KIR and class-I HLA molecules exhibit …
exercising cytotoxicity to eliminate tumor cells. Both KIR and class-I HLA molecules exhibit …
The impact of killer cell immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) class I ligands on predisposition or protection against prostate …
Natural killer (NK) cell development largely depends on killer cell immunoglobulin-like
receptors (KIRs) and human leukocyte antigen (HLA) class I ligands. In the current study, we …
receptors (KIRs) and human leukocyte antigen (HLA) class I ligands. In the current study, we …
[PDF][PDF] Expression of Killer Cell Immunoglobulin-like Receptors (KIR) in Sex-associated Malignancies.
N Hassan, L Le Jie, TJ Hao, SZ Idris… - Malaysian Journal of …, 2022 - medic.upm.edu.my
Introduction: Sex shapes immune response with possible consequence on tumor immune
escape. Acute lymphoblastic leukemia (ALL) predominates in males while ovarian cancer …
escape. Acute lymphoblastic leukemia (ALL) predominates in males while ovarian cancer …