Exosome mediated delivery of miR-124 promotes neurogenesis after ischemia

J Yang, X Zhang, X Chen, L Wang, G Yang - Molecular Therapy-Nucleic …, 2017 - cell.com
The intrinsic ability of neurogenesis after stroke has been proven weak, which results in
insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs …

The role of cadherin genes in five major psychiatric disorders: A literature update

Z Hawi, J Tong, C Dark, H Yates… - American Journal of …, 2018 - Wiley Online Library
Converging evidence from candidate gene, genome‐wide linkage, and association studies
support a role of cadherins in the pathophysiology of five major psychiatric disorders …

Oligodendroglioma: a review of management and pathways

M Bou Zerdan, HI Assi - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
Anaplastic oligodendrogliomas are a type of glioma that occurs primarily in adults but are
also found in children. These tumors are genetically defined according to the mutations they …

Dissecting neural differentiation regulatory networks through epigenetic footprinting

MJ Ziller, R Edri, Y Yaffe, J Donaghey, R Pop… - Nature, 2015 - nature.com
Abstract Models derived from human pluripotent stem cells that accurately recapitulate
neural development in vitro and allow for the generation of specific neuronal subtypes are of …

Differential expression of novel potential regulators in hematopoietic stem cells

EC Forsberg, SS Prohaska, S Katzman… - PLoS …, 2005 - journals.plos.org
The hematopoietic system is an invaluable model both for understanding basic
developmental biology and for developing clinically relevant cell therapies. Using highly …

Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

D Liang, AL Elwell, N Aygün, O Krupa, JM Wolter… - Nature …, 2021 - nature.com
Common genetic risk for neuropsychiatric disorders is enriched in regulatory elements
active during cortical neurogenesis. However, it remains poorly understood as to how these …

The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors

A Flora, JJ Garcia, C Thaller… - Proceedings of the …, 2007 - National Acad Sciences
Proneural factors represent< 10 transcriptional regulators required for specifying all of the
different neurons of the mammalian nervous system. The mechanisms by which such a …

Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus

Y Yamawaki, M Fuchikami, S Morinobu… - The World Journal of …, 2012 - Taylor & Francis
Objectives. Epigenetic mechanisms, such as changes in gene expression resulting from
chromatin remodeling through histone acetylation, have been implicated in the …

tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing

L de la Fuente, Á Arzalluz-Luque, M Tardáguila… - Genome Biology, 2020 - Springer
Recent advances in long-read sequencing solve inaccuracies in alternative transcript
identification of full-length transcripts in short-read RNA-Seq data, which encourages the …

Language impairments in ASD resulting from a failed domestication of the human brain

A Benítez-Burraco, W Lattanzi, E Murphy - Frontiers in Neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing
social and cognitive deficits, including marked problems with language. Numerous genes …