The regenerative capacity of bone is indispensable for growth, given that accidental injury is
almost inevitable. Bone regenerative capacity is relevant for the aging population globally …

TiO2 nanostructures and more specifically nanotubes have gained significant attention in
biomedical applications, due to their controlled nanoscale topography in the sub-100 nm …

Mesenchymal stem cells (MSCs) play a major role in bone tissue engineering (BTE) thanks
to their capacity for osteogenic differentiation and being easily available. In vivo, MSCs are …

Since the piezoelectric quality of bone was discovered in 1957, scientists have applied
exogenous electrical stimulation for the purpose of healing. Despite the efforts made over …

Bioreactors have been employed in tissue engineering to sustain longer and larger cell
cultures, managing nutrient transfer and waste removal. Multiple designs have been …

An extensive research field in regenerative medicine is electrical stimulation (ES) and its
impact on tissue and cells. The mechanism of action of ES, particularly the role of electrical …

Cellular motility is essential for making and maintaining multicellular organisms throughout
their lifespan. Migrating cells can move either individually or collectively by a crawling …

Orthopedic fractures have a significant impact on patients in the form of economic loss and
functional impairment. Beyond the standard methods of reduction and fixation, one adjunct …

Abstract Capacitively Coupled (CCoupled) electric fields are used to stimulate cell cultures
in Tissue Engineering. Knowing the electric field (E-Field) magnitude in the culture medium …

Low-intensity pulsed ultrasound treatment is known to shorten the healing period of bone
fractures by 30%–40%, but the initial mechanism of the healing process remains unknown …