Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040

Y Xi, P Xu - Translational oncology, 2021 - Elsevier
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

BS Sheena, L Hiebert, H Han, H Ippolito… - The lancet …, 2022 - thelancet.com
Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …

Screening and prevention of colorectal cancer

P Kanth, JM Inadomi - Bmj, 2021 - bmj.com
Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites

Y Cao, J Oh, M Xue, WJ Huh, J Wang… - Science, 2022 - science.org
Microbiota-derived metabolites that elicit DNA damage can contribute to colorectal cancer
(CRC). However, the full spectrum of genotoxic chemicals produced by indigenous gut …

[HTML][HTML] Plant-derived bioactive compounds in colon cancer treatment: An updated review

A Esmeeta, S Adhikary, V Dharshnaa… - Biomedicine & …, 2022 - Elsevier
Colon cancer is the third most predominant cancer caused by genetic, environmental and
nutritional factors. Plant-based compounds are very well known to regress colon cancer in …

Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

R Sharma, M Abbasi-Kangevari… - The lancet …, 2022 - thelancet.com
Background Colorectal cancer is the third leading cause of cancer deaths worldwide. Given
the recent increasing trends in colorectal cancer incidence globally, up-to-date information …

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …

Early‐onset colorectal cancer in young individuals

G Mauri, A Sartore‐Bianchi, AG Russo… - Molecular …, 2019 - Wiley Online Library
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

Gastrointestinal cancers in China, the USA, and Europe

Y Xie, L Shi, X He, Y Luo - Gastroenterology report, 2021 - academic.oup.com
Gastrointestinal (GI) cancers, including colorectal cancer, gastric cancer, and esophageal
cancer, are a major medical and economic burden worldwide and have the largest number …