MiRNAs action and impact on mitochondria function, metabolic reprogramming and chemoresistance of cancer cells: a systematic review

D Rosolen, E Nunes-Souza, R Marchi, MV Tofolo… - Biomedicines, 2023 - mdpi.com
MicroRNAs (miRNAs) are involved in the regulation of mitochondrial function and
homeostasis, and in the modulation of cell metabolism, by targeting known oncogenes and …

Roles of noncoding RNAs in regulation of mitochondrial electron transport chain and oxidative phosphorylation

A Kobayashi, T Takeiwa, K Ikeda, S Inoue - International Journal of …, 2023 - mdpi.com
The mitochondrial electron transport chain (ETC) plays an essential role in energy
production by inducing oxidative phosphorylation (OXPHOS) to drive numerous biochemical …

MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells

Z Hu, N Linn, Q Li, K Zhang, J Liao, Q Han… - Science of The Total …, 2023 - Elsevier
Copper (Cu), an environmental heavy metal pollutant, has been widely researched in its
toxicology. Recently, an increasing number of mitochondrial microRNAs (mitomiRs) have …

Mitochondrial metabolism as a dynamic regulatory hub to malignant transformation and anti-cancer drug resistance

MS Tomar, A Kumar, A Shrivastava - Biochemical and biophysical research …, 2024 - Elsevier
Glycolysis is the fundamental cellular process that permits cancer cells to convert energy
and grow anaerobically. Recent developments in molecular biology have made it evident …

Diagnostic significance of dysregulated miRNAs in T-cell malignancies and their metabolic roles

D Mondal, S Shinde, S Paul, S Thakur… - Frontiers in …, 2023 - frontiersin.org
T-cell malignancy is a broad term used for a diverse group of disease subtypes representing
dysfunctional malignant T cells transformed at various stages of their clonal evolution …

Mitochondrial microRNA profiles are altered in thirteen-lined ground squirrels (Ictidomys tridecemlineatus) during hibernation

K Robichaud, B Duffy, JF Staples… - Physiological …, 2024 - journals.physiology.org
Thirteen-lined ground squirrels (TLGSs) are obligate hibernators that cycle between torpor
(low metabolic rate and body temperature) and interbout euthermia (IBE; typical euthermic …

Guidelines for mitochondrial RNA analysis

A Jusic, Z Erpapazoglou, LT Dalgaard… - … Therapy-Nucleic Acids, 2024 - cell.com
Mitochondria are the energy-producing organelles of mammalian cells with critical
involvement in metabolism and signaling. Studying their regulation in pathological …

Oleuropein activates autophagy to circumvent anti-plasmodial defense

P Sharma, N Tandel, R Kumar, S Negi, P Sharma… - Iscience, 2024 - cell.com
Antimalarial drug resistance and unavailability of effective vaccine warrant for newer drugs
and drug targets. Hence, anti-inflammatory activity of phyto-compound (oleuropein; OLP) …

Hexavalent-chromium-induced disruption of mitochondrial dynamics and apoptosis in the liver via the AMPK-PGC-1α pathway in ducks

C Wang, X Dai, C Xing, C Zhang, H Cao, X Guo… - International Journal of …, 2023 - mdpi.com
Hexavalent chromium (Cr (VI)) is a hazardous substance that poses significant risks to
environmental ecosystems and animal organisms. However, the specific consequences of …

Cytotoxic properties, glycolytic effects and high-resolution respirometry mitochondrial activities of Eriocephalus racemosus against MDA-MB 231 triple-negative …

F Adu-Amankwaah, C Februarie, K Nyambo… - … Medicine and Therapies, 2024 - Springer
Introduction Triple-negative breast cancer (TNBC) represents a significant global health
crisis due to its resistance to conventional therapies and lack of specific molecular targets …