• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Since the publication of the 2018 European Society of Cardiology/European Society of
Hypertension (ESC/ESH) Guidelines for the Management of Arterial Hypertension, several …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

BACKGROUND: Renal denervation (RDN) has demonstrated clinically relevant reductions
in blood pressure (BP) among individuals with uncontrolled hypertension despite lifestyle …

Renal nerves have critical roles in regulating blood pressure and fluid volume, and their
dysfunction is closely related with cardiovascular diseases. Renal nerves are composed of …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Importance Ultrasound renal denervation (uRDN) was shown to lower blood pressure (BP)
in patients with uncontrolled hypertension (HTN). Establishing the magnitude and …

Hypertension is a leading risk factor for cardiovascular morbidity and mortality. Despite the
widespread availability of both pharmacological and lifestyle therapeutic options, blood …

The efficacy of renal denervation has been controversial, but recent randomized sham-
controlled trials demonstrated significant blood pressure reductions after renal denervation …

Importance Although early trials of endovascular renal denervation (RDN) for patients with
resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was …