Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Resistin, a small secretory molecule, has been implicated to play an important role in the
development of insulin resistance under obese condition. For the past few decades, it has …

The challenge of rapid macromolecular synthesis enforces the energy-hungry cancer cell
mitochondria to switch their metabolic phenotypes, accomplished by activation of oncogenic …

Abstract The Resistin-Like Molecules (RELM) α, β, and γ and their namesake, resistin, share
structural and sequence homology but exhibit significant diversity in expression and function …

Systemic and organ-confined inflammation has been associated with cancer development
and progression. Resistin, initially described as an adipocyte-derived cytokine in mice, is …

As a member of the suppressor of cytokine signaling (SOCS) family, SOCS3 is a cytokine-
inducible protein that inhibits cytokine signaling in a variety of signaling pathways …

Background Colorectal cancer (CRC) is one of the most common cancers worldwide.
Circular RNAs (circRNAs), a novel class of non-coding RNAs, have been confirmed to be …

Chondrosarcoma is a common primary malignant tumor of the bone that can metastasize
through the vascular system to other organs. A key step in the metastatic process …

Lipid metabolism in cancer cells has garnered increasing attention in recent decades.
Cancer cells thrive in hypoxic conditions, nutrient deficiency, and oxidative stress and …