Physiology of iron metabolism

S Waldvogel-Abramowski, G Waeber… - Transfusion Medicine …, 2014 - karger.com
A revolution occurred during the last decade in the comprehension of the physiology as well
as in the physiopathology of iron metabolism. The purpose of this review is to summarize the …

[HTML][HTML] Sport nutrigenomics: personalized nutrition for athletic performance

NS Guest, J Horne, SM Vanderhout… - Frontiers in nutrition, 2019 - frontiersin.org
An individual's dietary and supplement strategies can influence markedly their physical
performance. Personalized nutrition in athletic populations aims to optimize health, body …

The Rotterdam Study: 2018 update on objectives, design and main results

MA Ikram, GGO Brusselle, SD Murad… - European journal of …, 2017 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Systematic identification of trans eQTLs as putative drivers of known disease associations

HJ Westra, MJ Peters, T Esko, H Yaghootkar… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta …

Genome-wide associations for birth weight and correlations with adult disease

M Horikoshi, RN Beaumont, FR Day, NM Warrington… - Nature, 2016 - nature.com
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …

Contrasting the genetic architecture of 30 complex traits from summary association data

H Shi, G Kichaev, B Pasaniuc - The American Journal of Human Genetics, 2016 - cell.com
Variance-component methods that estimate the aggregate contribution of large sets of
variants to the heritability of complex traits have yielded important insights into the genetic …

Mapping and analysis of chromatin state dynamics in nine human cell types

J Ernst, P Kheradpour, TS Mikkelsen, N Shoresh… - Nature, 2011 - nature.com
Chromatin profiling has emerged as a powerful means of genome annotation and detection
of regulatory activity. The approach is especially well suited to the characterization of non …

Genetic diversity and association studies in US Hispanic/Latino populations: applications in the Hispanic Community Health Study/Study of Latinos

MP Conomos, CA Laurie, AM Stilp, SM Gogarten… - The American Journal of …, 2016 - cell.com
US Hispanic/Latino individuals are diverse in genetic ancestry, culture, and environmental
exposures. Here, we characterized and controlled for this diversity in genome-wide …

The Rotterdam Study: 2016 objectives and design update

A Hofman, GGO Brusselle, SD Murad… - European journal of …, 2015 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Natural selection on EPAS1 (HIF2α) associated with low hemoglobin concentration in Tibetan highlanders

CM Beall, GL Cavalleri, L Deng… - Proceedings of the …, 2010 - National Acad Sciences
By impairing both function and survival, the severe reduction in oxygen availability
associated with high-altitude environments is likely to act as an agent of natural selection …