This review summarizes our current understanding of the major pathway for the initiation
phase of protein synthesis in eukaryotic cells, with a focus on recent advances. We describe …

Bacteria often encounter temperature fluctuations in their natural habitats and must adapt to
survive. The molecular response of bacteria to sudden temperature upshift or downshift is …

RNA helicases of the DEAD box family are present in all eukaryotic cells and in many
bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism …

Acinetobacter baumannii is a common cause of serious nosocomial infections. Although
community-acquired infections are observed, the vast majority occur in people with …

▪ Abstract Eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that mediates
recruitment of ribosomes to mRNA. This event is the rate-limiting step for translation under …

Oncogenic activation of the proto-oncogene c-abl in human leukemias occurs as a result of
the addition of exons from the gene bcr and truncation of the first abl exon. Analysis of …

DNA and RNA helicases are ubiquitous enzymes that mediate the nucleoside-triphosphate-
dependent unwinding of nucleic acid duplexes, a necessary step in genome replication …

RNA helicases of the DEAD-box protein family have been shown to participate in every
aspect of RNA metabolism. They are present in most organisms where they work as RNA …

The assembly of ribosomes from a discrete set of components is a key aspect of the highly
coordinated process of ribosome biogenesis. In this review, we present a brief history of the …

RNA helicases from the DEAD-box family are found in almost all organisms and have
important roles in RNA metabolism. They are associated with many processes ranging from …