THE PAST decade has witnessed an upsurge in our understanding of the hypothalamic
regulation of appetite. Expression of appetite or the motivational drive toward an energy …

Our understanding of the physiological systems that regulate food intake and body weight
has increased immensely over the past decade. Brain centres, including the hypothalamus …

The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …

Several lines of investigation suggest that the hypothalamic neuropeptide melanin-
concentrating hormone (MCH) regulates body weight in mammals. Obese mice lacking …

Our knowledge of the physiological systems controlling energy homeostasis has increased
dramatically over the last decade. The roles of peripheral signals from adipose tissue …

The last decade has witnessed a marked increase in our understanding of the importance of
gut hormones in the regulation of energy homeostasis. In particular, the discovery that the …

Feeding in mammals is a periodic behavior; however, knowledge of how the brain signals
an intermittent eating pattern is scanty. Recent indirect evidence indicates that one of the …

Abstract Steroidogenic factor 1 (SF-1)-expressing neurons of the ventromedial
hypothalamus (VMH) control energy homeostasis, but the role of insulin action in these cells …

8.2. Effects in the pancreas 8.3. Effects on the intestinal sphincter 8.4. Effects on intestinal
motility 8.5. Effects on intestinal cellular proliferation 8.6. Effects on intestinal fluid and ion …

There is a growing worldwide epidemic of obesity. Obese people have a higher incidence of
type 2 diabetes and cardiovascular disease, and hence present increasing social, financial …