The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

Improved hygiene leading to reduced exposure to microorganisms has been implicated as
one possible cause for the recent “epidemic” of chronic inflammatory diseases (CIDs) in …

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

An increased intestinal permeability has been described in various gastrointestinal and non-
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …

A fundamental function of the intestinal epithelium is to act as a barrier that limits interactions
between luminal contents such as the intestinal microbiota, the underlying immune system …

Coeliac disease is an immune-mediated enteropathy against dietary gluten present in
wheat, rye and barley and is one of the most common lifelong food-related disorders …

A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium
with its barrier function is in charge of a tightly controlled antigen trafficking from the …

There is a need for consensus on the recommendations for follow-up of children and
adolescents with celiac disease. Objectives: To gather the current evidence and to offer …

Type 1 diabetes (T1D) is a multifactorial autoimmune disease driven by T-cells against the
insulin-producing islet β-cells, resulting in a marked loss of β-cell mass and function …