Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases

BC Melnik - Journal of translational medicine, 2015 - Springer
Single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity-
associated) gene are associated with enhanced FTO expression, increased body weight …

[HTML][HTML] Prolactin-induced protein (PIP)-characterization and role in breast cancer progression

A Urbaniak, K Jablonska… - American journal of …, 2018 - ncbi.nlm.nih.gov
Prolactin-induced protein (PIP) is a small secreted glycoprotein carrying several N-linked
carbohydrate chains. The expression of PIP is generally restricted to cells with apocrine …

Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2

NO Chimge, SK Baniwal, GH Little, Y Chen… - Breast cancer …, 2011 - Springer
Introduction In contrast to its role in breast cancer (BCa) initiation, estrogen signaling has a
protective effect in later stages, where estrogen receptor (ER) α loss associates with …

Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15

J Lehmann-Che, AS Hamy, R Porcher… - Breast Cancer …, 2013 - Springer
Introduction Molecular apocrine (MA) tumors are estrogen receptor (ER) negative breast
cancers characterized by androgen receptor (AR) expression. We analyzed a group of 58 …

Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs

TP Knutson, TH Truong, S Ma, NJ Brady… - Journal of Hematology & …, 2017 - Springer
Background Estrogen and progesterone are potent breast mitogens. In addition to steroid
hormones, multiple signaling pathways input to estrogen receptor (ER) and progesterone …

Characterisation of GATA3 expression in invasive breast cancer: differences in histological subtypes and immunohistochemically defined molecular subtypes

T Shaoxian, Y Baohua, X Xiaoli, C Yufan… - Journal of Clinical …, 2017 - jcp.bmj.com
Aims GATA-binding protein 3 (GATA3) is a sensitive and relatively specific marker in breast
and urothelial carcinomas. Its diagnostic utility in primary and metastatic breast cancers has …

Prolactin-Induced Protein is a novel biomarker for Keratoconus

R Sharif, S Bak-Nielsen, H Sejersen, K Ding… - Experimental eye …, 2019 - Elsevier
Purpose The purpose of the study was to investigate the role of Prolactin-Induced Protein
(PIP) as a predictive biomarker for Keratoconus (KC). Participants This study included one …

Role of Runx2 in breast cancer-mediated bone metastasis

M Vishal, R Swetha, G Thejaswini, B Arumugam… - International journal of …, 2017 - Elsevier
Breast cancer is one of the most prevalent forms of cancer in women. The currently available
treatment for breast cancer is mostly curative except when it becomes metastatic. One of the …

Additive effect of the AZGP1, PIP, S100A8 and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma

TZ Parris, A Kovács, L Aziz, S Hajizadeh… - … journal of cancer, 2014 - Wiley Online Library
The deregulation of key cellular pathways is fundamental for the survival and expansion of
neoplastic cells, which in turn can have a detrimental effect on patient outcome. To develop …

Strategy for SRM-based verification of biomarker candidates discovered by iTRAQ method in limited breast cancer tissue samples

S Muraoka, H Kume, S Watanabe… - Journal of proteome …, 2012 - ACS Publications
Since LC–MS-based quantitative proteomics has become increasingly applied to a wide
range of biological applications over the past decade, numerous studies have performed …