Comparative analysis of BTK inhibitors and mechanisms underlying adverse effects
HY Estupiñán, A Berglöf, R Zain… - Frontiers in cell and …, 2021 - frontiersin.org
The cytoplasmic protein-tyrosine kinase BTK plays an essential role for differentiation and
survival of B-lineage cells and, hence, represents a suitable drug target. The number of BTK …
survival of B-lineage cells and, hence, represents a suitable drug target. The number of BTK …
[HTML][HTML] The broad spectrum of lung diseases in primary antibody deficiencies
Human primary immunodeficiency diseases (PIDs) represent a heterogeneous group of
more than 350 disorders. They are rare diseases, but their global incidence is more relevant …
more than 350 disorders. They are rare diseases, but their global incidence is more relevant …
IVIg use associated with ten-fold reduction of serious infections in multiple myeloma patients treated with anti-BCMA bispecific antibodies
BCMA-targeted bispecific antibodies (BiAb) are efficacious in relapsed/refractory multiple
myeloma; however, serious infections have emerged as important toxicities. In this …
myeloma; however, serious infections have emerged as important toxicities. In this …
Severe COVID-19 in patients with B cell alymphocytosis and response to convalescent plasma therapy
Discussion We describe two cases of severe COVID-19 with ARDS in patients with
hypogammaglobulinemia and B cell alymphocytosis. One patient died despite mechanical …
hypogammaglobulinemia and B cell alymphocytosis. One patient died despite mechanical …
Of mycelium and men: inherent human susceptibility to fungal diseases
DC Vinh - Pathogens, 2023 - mdpi.com
In medical mycology, the main context of disease is iatrogenic-based disease. However,
historically, and occasionally, even today, fungal diseases affect humans with no obvious …
historically, and occasionally, even today, fungal diseases affect humans with no obvious …
[HTML][HTML] Targeting Bruton's tyrosine kinase (BTK) as a signaling pathway in immune-mediated diseases: from molecular mechanisms to leading treatments
GM Tavakoli, N Yazdanpanah… - Advances in Rheumatology, 2024 - SciELO Brasil
Bruton's tyrosine kinase (BTK), a nonreceptor tyrosine kinase, plays a remarkable role in the
transmission and amplification of extracellular signals to intracellular signaling pathways …
transmission and amplification of extracellular signals to intracellular signaling pathways …
Susceptibility to Cryptococcus neoformans Infection with Bruton's Tyrosine Kinase Inhibition
JA Messina, CD Giamberardino, JL Tenor… - Infection and …, 2023 - Am Soc Microbiol
Patients receiving the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib have an increased
likelihood of fungal infections. The objectives of this study were to determine if Cryptococcus …
likelihood of fungal infections. The objectives of this study were to determine if Cryptococcus …
Chronic Aichi virus infection in a patient with X-linked agammaglobulinemia
G Bucciol, L Moens, K Payne, E Wollants… - Journal of clinical …, 2018 - Springer
progressive nephromegaly, and refractory temporal lobe epilepsy (detailed clinical history
can be found in this article's supplemental data). Blood analysis showed progressive …
can be found in this article's supplemental data). Blood analysis showed progressive …
Appropriate lung management in patients with primary antibody deficiencies
Introduction: Human primary immunodeficiency diseases (PIDs) include a broad spectrum of
more than 350 disorders, involving different branches of the immune system and classified …
more than 350 disorders, involving different branches of the immune system and classified …
Ibrutinib in primary central nervous system diffuse large B-cell lymphoma
JT Low, KB Peters - CNS oncology, 2020 - Taylor & Francis
The standard regimen for the treatment of newly diagnosed primary CNS lymphoma
(PCNSL) remains regimens that contain high-dose methotrexate (MTX). While these …
(PCNSL) remains regimens that contain high-dose methotrexate (MTX). While these …