Molecular epidemiology and evolution of Haemophilus influenzae

S Wen, D Feng, D Chen, L Yang, Z Xu - Infection, Genetics and Evolution, 2020 - Elsevier
Haemophilus influenzae remains a common cause of illness in children worldwide. H.
influenzae type b is the leading cause of bacterial meningitis in children before introduction …

The role of the methoxy group in approved drugs

D Chiodi, Y Ishihara - European Journal of Medicinal Chemistry, 2024 - Elsevier
The methoxy substituent is prevalent in natural products and, consequently, is present in
many natural product-derived drugs. It has also been installed in modern drug molecules …

Meropenem combined with ciprofloxacin combats hypermutable Pseudomonas aeruginosa from respiratory infections of cystic fibrosis patients

VE Rees, R Yadav, KE Rogers, JB Bulitta… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Hypermutable Pseudomonas aeruginosa organisms are prevalent in chronic respiratory
infections and have been associated with reduced lung function in cystic fibrosis (CF); these …

Optimization and evaluation of piperacillin-tobramycin combination dosage regimens against Pseudomonas aeruginosa for patients with altered pharmacokinetics via …

R Yadav, KE Rogers, PJ Bergen… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Augmented renal clearance (ARC) in critically ill patients can result in suboptimal drug
exposures and treatment failure. Combination dosage regimens accounting for ARC have …

Molecular characterization of fluoroquinolones, macrolides, and imipenem resistance in Haemophilus influenzae: analysis of the mutations in QRDRs and …

A Cherkaoui, N Gaïa, D Baud, S Leo, A Fischer… - European Journal of …, 2018 - Springer
The aims of the present study were to characterize the mechanisms of resistance to
fluoroquinolones, macrolides, and imipenem in Haemophilus influenzae, to assess the …