Male infertility: a public health issue caused by sexually transmitted pathogens

F Gimenes, RP Souza, JC Bento, JJV Teixeira… - Nature Reviews …, 2014 - nature.com
Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria,
viruses and protozoa, and can induce male infertility through multiple pathophysiological …

Viral threat to male fertility

W Liu, R Han, H Wu, D Han - Andrologia, 2018 - Wiley Online Library
The detrimental effects of Zika virus (ZIKV) infection on mouse testicular functions have
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …

Progresses on three pattern recognition receptor families (TLRs, RLRs and NLRs) in teleost

Z Liao, J Su - Developmental & Comparative Immunology, 2021 - Elsevier
Pattern recognition receptors (PRRs) are a class of immune sensors that play crucial roles in
detecting and responding to the conserved patterns of microorganisms. To date, many …

Toll-like receptors (TLR) 2 and 4 on human sperm recognize bacterial endotoxins and mediate apoptosis

Y Fujita, T Mihara, T Okazaki, M Shitanaka… - Human …, 2011 - academic.oup.com
BACKGROUND Bacterial infections of the genital tract are one of the most serious causes of
infertility in males. In some human patients with poor semen quality, leukocytospermia has …

Targeting Trojan Horse leukocytes for HIV prevention

DJ Anderson, JA Politch, AM Nadolski, CD Blaskewicz… - Aids, 2010 - journals.lww.com
Targeting Trojan Horse leukocytes for HIV prevention : AIDS Targeting Trojan Horse leukocytes
for HIV prevention : AIDS Log in or Register Subscribe to journalSubscribe Get new issue …

Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells

A Ceballos, F Remes Lenicov, J Sabatté… - Journal of Experimental …, 2009 - rupress.org
Semen is the main vector for HIV-1 dissemination worldwide. It contains three major sources
of infectious virus: free virions, infected leukocytes, and spermatozoa-associated virions. We …

Potential for virus endogenization in humans through testicular germ cell infection: the case of HIV

D Mahé, G Matusali, C Deleage… - Journal of …, 2020 - Am Soc Microbiol
Viruses have colonized the germ line of our ancestors on several occasions during
evolution, leading to the integration in the human genome of viral sequences from over 30 …

In vitro human immunodeficiency virus and sperm cell interaction mediated by the mannose receptor

W Cardona-Maya, PA Velilla, CJ Montoya… - Journal of reproductive …, 2011 - Elsevier
Leukocytes are considered to be the main source of HIV-1 infection in semen. However, HIV-
1 interaction with spermatozoa has also been demonstrated, suggesting that both …

HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDS

H Li, CD Pauza - Blood, The Journal of the American Society of …, 2011 - ashpublications.org
HIV infects and replicates in CD4+ T cells but effects on host immunity and disease also
involve depletion, hyper-activation, and modification of CD4-negative cell populations. In …

Presence of HIV-1 DNA in spermatozoa from HIV-positive patients: changes in the semen parameters

W Cardona-Maya, P Velilla, CJ Montoya… - Current HIV …, 2009 - ingentaconnect.com
Although very inefficient, sexual transmission of HIV-1 is responsible for more than 80% of
infections worldwide. Yet, the presence of HIV in spermatozoa has been a matter of debate …