Sex differences in HIV infection

EP Scully - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review This review will outline the multilevel effects of biological sex on
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …

Hormonal contraception and HIV-1 acquisition: biological mechanisms

JP Hapgood, C Kaushic, Z Hel - Endocrine reviews, 2018 - academic.oup.com
Access to effective affordable contraception is critical for individual and public health. A wide
range of hormonal contraceptives (HCs), which differ in composition, concentration of the …

Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women

LR McKinnon, LJ Liebenberg, N Yende-Zuma… - Nature medicine, 2018 - nature.com
Several clinical trials have demonstrated that antiretroviral (ARV) drugs taken as pre-
exposure prophylaxis (PrEP) can prevent HIV infection, with the magnitude of protection …

The initial interplay between HIV and mucosal innate immunity

V Caputo, M Libera, S Sisti, B Giuliani… - Frontiers in …, 2023 - frontiersin.org
Human Immunodeficiency Virus (HIV) is still one of the major global health issues, and
despite significant efforts that have been put into studying the pathogenesis of HIV infection …

The HIV-1 transmission bottleneck

SM Kariuki, P Selhorst, KK Ariën, JR Dorfman - Retrovirology, 2017 - Springer
It is well established that most new systemic infections of HIV-1 can be traced back to one or
a limited number of founder viruses. Usually, these founders are more closely related to …

[HTML][HTML] Microbiota-derived short chain fatty acids: Their role and mechanisms in viral infections

C Feng, C Jin, K Liu, Z Yang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Microbiota-derived short-chain fatty acids (SCFAs) are crucial for protecting the intestinal
barrier and regulating the immune response during infections. Recent studies show that viral …

[HTML][HTML] Beyond the barrier: female genital schistosomiasis as a potential risk factor for HIV-1 acquisition

AS Sturt, EL Webb, SC Francis, RJ Hayes… - Acta tropica, 2020 - Elsevier
Female genital schistosomiasis (FGS) results from egg-deposition in the female reproductive
tract primarily by the waterborne parasite Schistosoma (S.) haematobium, and less …

Short-chain fatty acids impair neutrophil antiviral function in an age-dependent manner

FJ Carrillo-Salinas, S Parthasarathy, L Moreno de Lara… - Cells, 2022 - mdpi.com
Half of the people living with HIV are women. Younger women remain disproportionally
affected in endemic areas, but infection rates in older women are rising worldwide. The …

The Mtb-HIV Syndemic Interaction: Why Treating M. tuberculosis Infection May Be Crucial for HIV-1 Eradication

R Waters, M Ndengane, MR Abrahams… - Future …, 2020 - Taylor & Francis
Accelerated tuberculosis and AIDS progression seen in HIV-1 and Mycobacterium
tuberculosis (Mtb)-coinfected individuals indicates the important interaction between these …

Bright Semiconductor Quantum Dots Shed New Light on Precision Nanomedicine for Various Diseases

P Zhang, M Jiao, Y Li, X Ding, KJ McHugh… - Small Science, 2024 - Wiley Online Library
Nanomaterials with diagnostic and therapeutic functions have exciting potential to reshape
the landscape of precision medicine. Impressive progress has been made toward the design …