Updated meta‐analysis of classical fear conditioning in the anxiety disorders

P Duits, DC Cath, S Lissek, JJ Hox… - Depression and …, 2015 - Wiley Online Library
The aim of the current study was twofold:(1) to systematically examine differences in fear
conditioning between anxiety patients and healthy controls using meta‐analytic methods …

The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research

A Pittig, M Treanor, RT LeBeau, MG Craske - … & Biobehavioral Reviews, 2018 - Elsevier
Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Genetic differences associated with dopamine and serotonin release mediate fear-induced bradycardia in the human brain

S Battaglia, C Nazzi, JF Thayer - Translational psychiatry, 2024 - nature.com
Fear-induced bradycardia, a transient heartbeat deceleration following exposure to threat, is
a physiological index observable in humans, especially in fear conditioning experiments …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Stress and fear extinction

S Maren, A Holmes - Neuropsychopharmacology, 2016 - nature.com
Stress has a critical role in the development and expression of many psychiatric disorders,
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …

A contemporary learning theory perspective on the etiology of anxiety disorders: it's not what you thought it was.

S Mineka, R Zinbarg - American psychologist, 2006 - psycnet.apa.org
The authors describe how contemporary learning theory and research provide the basis for
perspectives on the etiology and maintenance of anxiety disorders that capture the …

Trauma exposure and post‐traumatic stress disorder in the general population

Ö Frans, PA Rimmö, L Åberg… - Acta psychiatrica …, 2005 - Wiley Online Library
Objective: To examine the lifetime prevalence of trauma experiences and post‐traumatic
stress disorder (PTSD). Method: Questionnaire‐assessed PTSD, the type of traumatic event …

The role of Serotonin in fear learning and memory: A systematic review of human studies

F Tortora, AL Hadipour, S Battaglia, A Falzone… - Brain Sciences, 2023 - mdpi.com
Fear is characterized by distinct behavioral and physiological responses that are essential
for the survival of the human species. Fear conditioning (FC) serves as a valuable model for …

The study of fear extinction: implications for anxiety disorders

BM Graham, MR Milad - American Journal of Psychiatry, 2011 - Am Psychiatric Assoc
In this review, the authors propose that the fear extinction model can be used as an
experimental tool to cut across symptom dimensions of multiple anxiety disorders to …

Current status on behavioral and biological markers of PTSD: a search for clarity in a conflicting literature

PR Zoladz, DM Diamond - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Extensive research has identified stereotypic behavioral and biological abnormalities in post-
traumatic stress disorder (PTSD), such as heightened autonomic activity, an exaggerated …