Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …
is involved in several cancer developments, including NSCLC. The EGFR pathway …
[HTML][HTML] Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches
H Shabani, MH Karami, J Kolour, Z Sayyahi… - Biomedicine & …, 2023 - Elsevier
The rising incidence of breast cancer has been a significant source of concern in the
medical community. Regarding the adverse effects and consequences of current treatments …
medical community. Regarding the adverse effects and consequences of current treatments …
[HTML][HTML] The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies
M Butnariu, C Quispe, J Herrera-Bravo, P Helon… - Biomedicine & …, 2022 - Elsevier
Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …
Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis
M Homayoonfal, Z Asemi, B Yousefi - Cellular & Molecular Biology Letters, 2022 - Springer
Despite great advances, therapeutic approaches of osteosarcoma, the most prevalent class
of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to …
of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to …
Herbal therapies for cancer treatment: A review of phytotherapeutic efficacy
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …
chemical structures and bioactivity. This review examines their central role in cancer …
Therapeutic implications and clinical manifestations of thymoquinone
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …
Royal jelly: Beneficial properties and synergistic effects with chemotherapeutic drugs with particular emphasis in anticancer strategies
Cancer is one of the major causes of death globally. Currently, various methods are used to
treat cancer, including radiotherapy, surgery, and chemotherapy, all of which have serious …
treat cancer, including radiotherapy, surgery, and chemotherapy, all of which have serious …
How drug repurposing can advance drug discovery: challenges and opportunities
Traditional de novo drug discovery, which typically presents an 11% approval rate from
phase I trials and even higher failure rates in fields like neurodegeneration, often requires …
phase I trials and even higher failure rates in fields like neurodegeneration, often requires …
[HTML][HTML] Exploring the Therapeutic Potential of 5-Fluorouracil-Loaded Calcium Carbonate Nanoparticles Combined with Natural Compound Thymoquinone for Colon …
Given the need for novel and effective therapies for colon cancer, this study aimed to
investigate the effects of 5-fluorouracil-loaded calcium carbonate nanoparticles (5FU …
investigate the effects of 5-fluorouracil-loaded calcium carbonate nanoparticles (5FU …
Phytochemicals for the prevention and treatment of renal cell carcinoma: preclinical and clinical evidence and molecular mechanisms
EM Bajalia, FB Azzouz, DA Chism, DM Giansiracusa… - Cancers, 2022 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is the most frequently diagnosed kidney
cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an …
cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an …