DNA-encoded chemical libraries (DELs) represent a versatile and powerful technology
platform for the discovery of small-molecule ligands to protein targets of biological and …

DNA-encoded chemical libraries (DELs) have emerged as a powerful technology in drug
discovery. The wide adoption of DELs in the pharmaceutical industry and the rapid …

Phosphate linkages govern life as we know it. Their unique properties provide the
foundation for many natural systems from cell biology and biosynthesis to the backbone of …

Amino acids (AAs) are key structural motifs with widespread applications in organic
synthesis, biochemistry, and material sciences. Recently, with the development of milder …

DNA-encoded library (DEL) technology features a time-and cost-effective interrogation
format for the discovery of therapeutic candidates in the pharmaceutical industry. To develop …

DNA-encoded libraries of organic, synthesized molecules are an emerging technology for
target-based compound screening. The design of first generation encoded libraries placed …

Alcohols are among the most widely occurring functional groups found in naturally
abundant, biologically relevant organic compounds, which in many cases are considered …

DNA-encoded chemical libraries (DELs) have become a powerful technology platform in
drug discovery. Dual-pharmacophore DELs display two sets of small molecules at the …

Conspectus In the past two decades, a DNA-encoded chemical library (DEL or DECL) has
emerged and has become a major technology platform for ligand discovery in drug …

DNA-encoded library (DEL) technology is a novel ligand identification strategy that allows
the synthesis and screening of unprecedented chemical diversity more efficiently than …