The interplay between m6A RNA methylation and noncoding RNA in cancer
S Ma, C Chen, X Ji, J Liu, Q Zhou, G Wang… - Journal of hematology & …, 2019 - Springer
Abstract N6-methyladenosine (m6A) methylation, one of the most common RNA
modifications, has been reported to execute important functions that affect normal life …
modifications, has been reported to execute important functions that affect normal life …
Akt in cancer: Mediator and more
S Revathidevi, AK Munirajan - Seminars in cancer biology, 2019 - Elsevier
Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …
The relation between PI3K/AKT signalling pathway and cancer
Abstract Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular
signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling …
signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling …
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …
WBSMDA: within and between score for MiRNA-disease association prediction
Increasing evidences have indicated that microRNAs (miRNAs) are functionally associated
with the development and progression of various complex human diseases. However, the …
with the development and progression of various complex human diseases. However, the …
EGBMMDA: extreme gradient boosting machine for MiRNA-disease association prediction
Associations between microRNAs (miRNAs) and human diseases have been identified by
increasing studies and discovering new ones is an ongoing process in medical laboratories …
increasing studies and discovering new ones is an ongoing process in medical laboratories …
MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
[HTML][HTML] Exosomes from MiR-126-overexpressing adscs are therapeutic in relieving acute myocardial ischaemic injury
Q Luo, D Guo, G Liu, G Chen, M Hang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Recent studies have indicated that exosomes play an important role in
adipose-derived stem cell (ADSC) transplant-mediated ischaemic heart disease therapy …
adipose-derived stem cell (ADSC) transplant-mediated ischaemic heart disease therapy …
Metastasis: from dissemination to organ-specific colonization
Metastasis to distant organs is an ominous feature of most malignant tumours but the natural
history of this process varies in different cancers. The cellular origin, intrinsic properties of …
history of this process varies in different cancers. The cellular origin, intrinsic properties of …
Portrait of the PI3K/AKT pathway in colorectal cancer
SA Danielsen, PW Eide, A Nesbakken, T Guren… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Abstract PI3K/AKT signaling leads to reduced apoptosis, stimulates cell growth and
increases proliferation. Under normal conditions, PI3K/AKT activation is tightly controlled …
increases proliferation. Under normal conditions, PI3K/AKT activation is tightly controlled …