Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Cardiovascular disease—a leading cause of morbidity and mortality among adults—is
strongly influenced by platelet function through acute thrombotic and atherogenic …

ComiR is a web tool for combinatorial microRNA (miRNA) target prediction. Given an
messenger RNA (mRNA) in human, mouse, fly or worm genomes, ComiR computes the …

Blood platelet RNA-sequencing is increasingly used among the scientific community.
Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but …

The role of platelets in regulating vascular homeostasis has expanded beyond mediation of
haemostasis and thrombosis. The discovery of platelet RNA and the presence of …

Platelets are anucleate cytoplasmic fragments that lack genomic DNA, but continue to
synthesize protein using a pool of messenger RNAs (mRNAs), ribosomes, and regulatory …

Circulating microRNAs (miRNAs) have been reported as biomarkers for disease diagnosis.
RT‐qPCR is most commonly used to detect miRNAs; however, no consensus on the most …

Background and Objectives: Sickle cell disorder (SCD) is a paradigmatic example of a
complex monogenic disorder. SCD is characterized by the production of abnormal …

Hematopoietic PBX interacting protein (HPIP or pre-B-cell leukemia transcription factor
interacting protein (PBXIP1) was discovered two decades ago as a corepressor of pre-B-cell …

Abstract MicroRNAs (miRNAs) are short~ 22-nucleotide noncoding RNA that have been
found to influence the expression of many genes and cellular processes by either repressing …