Spheroids and organoids are cellular aggregates formed by multicellular culture under 3D
matrix microenvironment in vitro, capable of recapitulating partial structures, functions and …

Background Maintaining the vitality and functionality of dental pulp is paramount for tooth
integrity, longevity, and homeostasis. Aiming to treat irreversible pulpitis and necrosis, there …

Periodontitis is a highly prevalent disease that damages the supporting tissues of a tooth,
including the alveolar bone. Alveolar bone loss owing to periodontitis is broadly categorized …

Poly (lactic-co-glycolic acid)(PLGA) is a widely used biodegradable and biocompatible
copolymer in drug delivery systems (DDSs). In this article, we highlight the critical …

Inspired by the extracellular matrix (ECM), biomaterials have emerged as promising
strategies in the biomedical research and engineering domain, offering unique …

Injectable biomaterials have garnered increasing attention for their potential and beneficial
applications in minimally invasive surgical procedures and tissue regeneration. Extracellular …

Cancer is a significant worldwide health concern, and there is a demand for ongoing
breakthroughs in treatment techniques. Microspheres are among the most studied drug …

Osteoarthritis (OA) is a chronic condition characterized by degeneration of the articular
cartilage and subsequent bone hyperplasia. With the increasing prevalence driven by …

Repairing critical size bone defects (CSBD) is a major clinical challenge and requires
effective intervention by biomaterial scaffolds. Inspired by the fact that the cartilaginous …

Porous gelatin microspheres (PGMs) are effective means to achieve controlled release and
rapid functional response of anthocyanins (ANCs). In this study, PGMs were developed by …