Collagen is the major component of the tumor microenvironment and participates in cancer
fibrosis. Collagen biosynthesis can be regulated by cancer cells through mutated genes …

The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …

Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …

Cancers are complex ecosystems composed of malignant cells embedded in an intricate
microenvironment made of different non-transformed cell types and extracellular matrix …

Background Collagens are the most abundant proteins in extra cellular matrix and important
components of tumor microenvironment. Recent studies have showed that aberrant …

Abstract Development of chemoresistance in breast cancer patients greatly increases
mortality. Thus, understanding mechanisms underlying breast cancer resistance to …

Cervical cancer (CC) is a major gynecological problem in developing and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …

Progression through dissemination to tumor-surrounding tissues and metastasis
development is a hallmark of cancer that requires continuous cell-to-cell interactions and …

Molecular patterns and pathways in idiopathic pulmonary fibrosis (IPF) have been
extensively investigated, but few studies have assimilated multiomic platforms to provide an …

MicroRNAs (miRNAs) are important molecular regulatorsof cellular signaling and behavior.
They alter gene expression by targeting messenger RNAs, including those encoding …