The mammalian cell cycle has been extensively studied regarding cancer etiology,
progression, and therapeutic intervention. The canonical cell cycle framework is supported …

D-type cyclins encode G1/S cell cycle checkpoint proteins, which play a crucial role in
defining cell cycle exit and progression. Precise control of cell cycle exit is vital during …

Activating molecule in Beclin-1-regulated autophagy protein 1 (Ambra1) is well known to
mediate the autophagy process and promote the formation of autophagosomes. In addition …

Throughout my PhD studies, in front of curious family members and friends, I often found
myself faced with the question,“How close are we to finding a cure for cancer?” However …

The Rab40 subfamily are unique small monomeric GTPases that form CRL5-based ubiquitin
E3 ligase complex and regulate ubiquitylation of specific target proteins. Recent studies …

AMBRA1 is a tumour suppressor protein that functions as a substrate receptor in the
ubiquitin conjugation system and regulates the stability of D-type cyclins and cell …