Dengue is a highly endemic infectious disease of the tropical countries and is rapidly
becoming a global burden. It is caused by any of the 4 serotypes of dengue virus and is …

Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases.
Each year, there are∼ 50 million dengue infections and∼ 500,000 individuals are …

Flaviviruses are known to cause a variety of diseases in humans in different parts of the
world. There are very limited numbers of antivirals to combat flavivirus infection, and …

Dengue viral infection has become an increasing global health concern with over two-fifths
of the world's population at risk of infection. It is the most rapidly spreading vector borne …

Neutralization of flaviviruses in vivo correlates with the development of an antibody
response against the viral envelope (E) protein. Previous studies demonstrated that …

Antibody protection against flaviviruses is associated with the development of neutralizing
antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) …

The Flavivirus genus of the Flaviviridae family includes 70 enveloped single-stranded-RNA
positive-sense viruses transmitted by arthropods. Among these viruses, there are a relevant …

Dengue represents a major public health problem of growing global importance. In the
absence of specific dengue therapeutics, strategies for disease control have increasingly …

Traditionally, the four dengue virus serotypes have been associated with fever, rash, and the
more severe forms, haemorrhagic fever and shock syndrome. As our knowledge as well as …

Dengue viruses (DENVs) are emerging, mosquito-borne flaviviruses which cause dengue
fever and dengue hemorrhagic fever. The DENV complex consists of 4 serotypes …