The influence of adverse childhood experiences in pain management: mechanisms, processes, and trauma-informed care
LV Tidmarsh, R Harrison, D Ravindran… - Frontiers in Pain …, 2022 - frontiersin.org
Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and
psychological health in adulthood. Though understanding and psychological management …
psychological health in adulthood. Though understanding and psychological management …
[HTML][HTML] Brain insulin signaling as a potential mediator of early life adversity effects on physical and mental health
B Alberry, PP Silveira - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
In numerous brain structures, insulin signaling modulates the homeostatic processes,
sensitivity to reward pathways, executive function, memory, and cognition. Through human …
sensitivity to reward pathways, executive function, memory, and cognition. Through human …
The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis
Abstract Background Adverse childhood experiences (ACEs) have been implicated in the
aetiology of a range of health outcomes, including multimorbidity. In this systematic review …
aetiology of a range of health outcomes, including multimorbidity. In this systematic review …
Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of …
Background Childhood adversity is a potent determinant of health across development and
is associated with altered DNA methylation signatures, which might be more common in …
is associated with altered DNA methylation signatures, which might be more common in …
Childhood maltreatment and longitudinal epigenetic aging: NIMHD social epigenomics program
Importance Child physical and emotional abuse and neglect may affect epigenetic
signatures of accelerated aging several years after the exposure. Objective To examine the …
signatures of accelerated aging several years after the exposure. Objective To examine the …
[HTML][HTML] The maltreated eco-phenotype of eating disorders: a new diagnostic specifier? A systematic review of the evidence and comprehensive description
This systematic review aimed to summarize the evidence on the existence of a distinct
phenotypic expression of Eating Disorders (EDs) associated with childhood maltreatment …
phenotypic expression of Eating Disorders (EDs) associated with childhood maltreatment …
The oxytocin system and early‐life experience‐dependent plastic changes
T Onaka, Y Takayanagi - Journal of Neuroendocrinology, 2021 - Wiley Online Library
Early‐life experience influences social and emotional behaviour in adulthood. Affiliative
tactile stimuli in early life facilitate the development of social and emotional behaviour …
tactile stimuli in early life facilitate the development of social and emotional behaviour …
[HTML][HTML] Transmission of the adverse consequences of childhood maltreatment across generations: Focus on gestational biology
Childhood maltreatment (CM) has well-established consequences for the mental and
physical health of the exposed individual. Accumulating evidence now suggests that the …
physical health of the exposed individual. Accumulating evidence now suggests that the …
Childhood trauma and epigenetics: state of the science and future
Abstract Purpose of Review There is a great deal of interest regarding the biological
embedding of childhood trauma and social exposures through epigenetic mechanisms …
embedding of childhood trauma and social exposures through epigenetic mechanisms …
Childhood maltreatment and DNA methylation: a systematic review
Child maltreatment (CM) encompasses sexual abuse, physical abuse, emotional abuse,
neglect, and exposure to domestic and family violence. Epigenetic research investigating …
neglect, and exposure to domestic and family violence. Epigenetic research investigating …