Infectious diseases are a major threat worldwide. With the alarming rise of antimicrobial
resistance and emergence of new potential pathogens, a better understanding of the …

The intestine performs functions central to human health by breaking down food and
absorbing nutrients while maintaining a selective barrier against the intestinal microbiome …

Abstract Chicken infection with Salmonella Typhimurium is an important source of foodborne
human diseases. Salmonella colonizes the avian intestinal tract and more particularly the …

Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted
extraordinary progress in Organ-on-Chip (OoC) technology, leading to the development of in …

The recent spike in the instances of complex physiological host-microbe interactions has
raised the demand for developing in vitro models that recapitulate the microbial …

Background and Aims Perianal fistula represents one of the most disabling manifestations of
Crohn′ s disease (CD) due to complete destruction of the affected mucosa, which is …

The gut microbiome (GM), the gut barrier, and the blood-brain barrier (BBB) are key
elements of the gut-brain axis (GBA). The advances in organ-on-a-chip and induced …

The knowledge about enteric viral infection has vastly increased over the last eight years
due to the development of intestinal organoids and enteroids that suppose a step forward …

The intestinal microenvironment represents a complex and dynamic ecosystem, comprising
a diverse range of epithelial and non-epithelial cells, a protective mucus layer, and a diverse …

Human-induced pluripotent stem cell-derived small intestinal epithelial cell (hiPSC-SIEC)
monolayers are useful in vitro models for evaluating the gut mucosal barrier; however, their …